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MMP23 matrix metallopeptidase 23 [ Canis lupus familiaris (dog) ]

Gene ID: 607187, updated on 5-Mar-2024

Summary

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Official Symbol
MMP23provided by VGNC
Official Full Name
matrix metallopeptidase 23provided by VGNC
Primary source
VGNC:VGNC:53425
See related
Ensembl:ENSCAFG00845015492
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
MMP23B
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (56895797..56899258)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (56769309..56772909)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (57168723..57172324)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (56886453..56890059)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (56778874..56782357)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111095962 Neighboring gene MIB E3 ubiquitin protein ligase 2 Neighboring gene cyclin dependent kinase 11 Neighboring gene solute carrier family 35 member E2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
matrix metalloproteinase-23
Names
matrix metallopeptidase 23B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    56895797..56899258
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038666375.1 → XP_038522303.1  matrix metalloproteinase-23 isoform X4

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8I3P0A3
    Conserved Domains (4) summary
    smart00408
    Location:239 → 299
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:181 → 215
    ShKT; ShK toxin domain
    cd00096
    Location:243 → 247
    Ig; Ig strand B [structural motif]
    cl00064
    Location:91 → 171
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

  2. XM_038666374.1 → XP_038522302.1  matrix metalloproteinase-23 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8I3P0A3
    Conserved Domains (4) summary
    smart00408
    Location:262 → 322
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:204 → 238
    ShKT; ShK toxin domain
    cd00096
    Location:266 → 270
    Ig; Ig strand B [structural motif]
    cl00064
    Location:91 → 194
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

  3. XM_038666373.1 → XP_038522301.1  matrix metalloproteinase-23 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8C0QZC9, A0A8I3P0A3
    Conserved Domains (4) summary
    smart00408
    Location:294 → 354
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:236 → 270
    ShKT; ShK toxin domain
    cd04278
    Location:91 → 235
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    cd00096
    Location:298 → 302
    Ig; Ig strand B [structural motif]

  4. XM_038666372.1 → XP_038522300.1  matrix metalloproteinase-23 isoform X1

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8I3P0A3
    Related
    ENSCAFP00845021746.1, ENSCAFT00845027636.1
    Conserved Domains (4) summary
    smart00408
    Location:317 → 377
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:259 → 293
    ShKT; ShK toxin domain
    cd04278
    Location:91 → 258
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    cd00096
    Location:321 → 325
    Ig; Ig strand B [structural motif]

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    56886453..56890059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038476501.1 → XP_038332429.1  matrix metalloproteinase-23 isoform X4

    Conserved Domains (4) summary
    smart00408
    Location:239 → 299
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:181 → 215
    ShKT; ShK toxin domain
    cd00096
    Location:243 → 247
    Ig; Ig strand B [structural motif]
    cl00064
    Location:91 → 171
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

  2. XM_038476500.1 → XP_038332428.1  matrix metalloproteinase-23 isoform X3

    Conserved Domains (4) summary
    smart00408
    Location:262 → 322
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:204 → 238
    ShKT; ShK toxin domain
    cd00096
    Location:266 → 270
    Ig; Ig strand B [structural motif]
    cl00064
    Location:91 → 194
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

  3. XM_038476499.1 → XP_038332427.1  matrix metalloproteinase-23 isoform X2

    Conserved Domains (4) summary
    smart00408
    Location:294 → 354
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:236 → 270
    ShKT; ShK toxin domain
    cd04278
    Location:91 → 235
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    cd00096
    Location:298 → 302
    Ig; Ig strand B [structural motif]

  4. XM_038476498.1 → XP_038332426.1  matrix metalloproteinase-23 isoform X1

    Conserved Domains (4) summary
    smart00408
    Location:317 → 377
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:259 → 293
    ShKT; ShK toxin domain
    cd04278
    Location:91 → 258
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    cd00096
    Location:321 → 325
    Ig; Ig strand B [structural motif]

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    56778874..56782357
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038601802.1 → XP_038457730.1  matrix metalloproteinase-23 isoform X4

    Conserved Domains (4) summary
    smart00408
    Location:239 → 299
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:181 → 215
    ShKT; ShK toxin domain
    cd00096
    Location:243 → 247
    Ig; Ig strand B [structural motif]
    cl00064
    Location:91 → 171
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

  2. XM_038601801.1 → XP_038457729.1  matrix metalloproteinase-23 isoform X3

    Conserved Domains (4) summary
    smart00408
    Location:262 → 322
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:204 → 238
    ShKT; ShK toxin domain
    cd00096
    Location:266 → 270
    Ig; Ig strand B [structural motif]
    cl00064
    Location:91 → 194
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

  3. XM_038601800.1 → XP_038457728.1  matrix metalloproteinase-23 isoform X2

    Conserved Domains (4) summary
    smart00408
    Location:294 → 354
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:236 → 270
    ShKT; ShK toxin domain
    cd04278
    Location:91 → 235
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    cd00096
    Location:298 → 302
    Ig; Ig strand B [structural motif]

  4. XM_038601799.1 → XP_038457727.1  matrix metalloproteinase-23 isoform X1

    Conserved Domains (4) summary
    smart00408
    Location:317 → 377
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:259 → 293
    ShKT; ShK toxin domain
    cd04278
    Location:91 → 258
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    cd00096
    Location:321 → 325
    Ig; Ig strand B [structural motif]

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    57168723..57172324
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038537637.1 → XP_038393565.1  matrix metalloproteinase-23 isoform X4

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8I3P0A3
    Conserved Domains (4) summary
    smart00408
    Location:239 → 299
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:181 → 215
    ShKT; ShK toxin domain
    cd00096
    Location:243 → 247
    Ig; Ig strand B [structural motif]
    cl00064
    Location:91 → 171
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

  2. XM_038537636.1 → XP_038393564.1  matrix metalloproteinase-23 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8I3P0A3
    Conserved Domains (4) summary
    smart00408
    Location:262 → 322
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:204 → 238
    ShKT; ShK toxin domain
    cd00096
    Location:266 → 270
    Ig; Ig strand B [structural motif]
    cl00064
    Location:91 → 194
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

  3. XM_038537635.1 → XP_038393563.1  matrix metalloproteinase-23 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8C0QZC9, A0A8I3P0A3
    Conserved Domains (4) summary
    smart00408
    Location:294 → 354
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:236 → 270
    ShKT; ShK toxin domain
    cd04278
    Location:91 → 235
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    cd00096
    Location:298 → 302
    Ig; Ig strand B [structural motif]

  4. XM_038537634.1 → XP_038393562.1  matrix metalloproteinase-23 isoform X1

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8I3P0A3
    Conserved Domains (4) summary
    smart00408
    Location:317 → 377
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:259 → 293
    ShKT; ShK toxin domain
    cd04278
    Location:91 → 258
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    cd00096
    Location:321 → 325
    Ig; Ig strand B [structural motif]

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    56769309..56772909
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038522097.1 → XP_038378025.1  matrix metalloproteinase-23 isoform X4

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8I3P0A3
    Conserved Domains (4) summary
    smart00408
    Location:239 → 299
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:181 → 215
    ShKT; ShK toxin domain
    cd00096
    Location:243 → 247
    Ig; Ig strand B [structural motif]
    cl00064
    Location:91 → 171
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

  2. XM_038522095.1 → XP_038378023.1  matrix metalloproteinase-23 isoform X3

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8I3P0A3
    Conserved Domains (4) summary
    smart00408
    Location:262 → 322
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:204 → 238
    ShKT; ShK toxin domain
    cd00096
    Location:266 → 270
    Ig; Ig strand B [structural motif]
    cl00064
    Location:91 → 194
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

  3. XM_005620395.4 → XP_005620452.1  matrix metalloproteinase-23 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8C0QZC9, A0A8I3P0A3
    Conserved Domains (4) summary
    smart00408
    Location:294 → 354
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:236 → 270
    ShKT; ShK toxin domain
    cd04278
    Location:91 → 235
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    cd00096
    Location:298 → 302
    Ig; Ig strand B [structural motif]

  4. XM_843797.6 → XP_848890.1  matrix metalloproteinase-23 isoform X1

    See identical proteins and their annotated locations for XP_848890.1

    UniProtKB/TrEMBL
    A0A8C0Q079, A0A8I3P0A3
    Conserved Domains (4) summary
    smart00408
    Location:317 → 377
    IGc2; Immunoglobulin C-2 Type
    smart00254
    Location:259 → 293
    ShKT; ShK toxin domain
    cd04278
    Location:91 → 258
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    cd00096
    Location:321 → 325
    Ig; Ig strand B [structural motif]
Nucleotide Protein
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