U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hint1-ps1 histidine triad nucleotide binding protein 1, pseudogene 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 60580, updated on 29-Feb-2024

Summary

Go to the top of the page Help
Official Symbol
Hint1-ps1provided by RGD
Official Full Name
histidine triad nucleotide binding protein 1, pseudogene 1provided by RGD
Primary source
RGD:620960
See related
Ensembl:ENSRNOG00000005630 AllianceGenome:RGD:620960
Gene type
pseudo
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Pkci; Hint1; Prkci; Hint1l
Summary
Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
4q31
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (93430947..93431521, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (92100994..92101568, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (93405665..93406239, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC134486588 Neighboring gene thyroid stimulating hormone receptor, pseudogene 1 Neighboring gene glutamate ionotropic receptor delta type subunit 2 Neighboring gene uncharacterized LOC120102493

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Atypical protein kinase C plays a critical role in protein transport from pre-Golgi intermediates. Tisdale EJ, et al. J Biol Chem, 2003 Sep 26. PMID 12871960
  2. Protein Kinase C- alpha/betaII, delta, and zeta/lambda involvement in ethanol-induced MAPK expression in vascular smooth muscle cells. Johnson AL, et al. Cell Mol Biol (Noisy-le-grand), 2007 May 15. PMID 17531159
  3. Rab2 interacts directly with atypical protein kinase C (aPKC) iota/lambda and inhibits aPKCiota/lambda-dependent glyceraldehyde-3-phosphate dehydrogenase phosphorylation. Tisdale EJ. J Biol Chem, 2003 Dec 26. PMID 14570876
  4. Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway. Zhang J, et al. J Biol Chem, 2004 May 21. PMID 15037605
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Ras, Mek, PKC iota, and Rac 1 are involved in PKCbetaII induction of cell invasiveness through a signal pathway
    Title: Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway.
  2. PKC is involved in ethanol-induced MAPK expression in vascular smooth muscle cells.
    Title: Protein Kinase C- alpha/betaII, delta, and zeta/lambda involvement in ethanol-induced MAPK expression in vascular smooth muscle cells.
  3. Atypical protein kinase C plays a critical role in protein transport from pre-Golgi intermediates.
    Title: Atypical protein kinase C plays a critical role in protein transport from pre-Golgi intermediates.
  4. protein kinase C iota/lambda binds to Rab 2, which inhibits aPKCiota/lambda-dependent GADPH phosphorylation
    Title: Rab2 interacts directly with atypical protein kinase C (aPKC) iota/lambda and inhibits aPKCiota/lambda-dependent glyceraldehyde-3-phosphate dehydrogenase phosphorylation.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Other Names

  • histidine triad nucleotide binding protein 1 pseudogene
  • protein kinase C inhibitor pseudogene
  • putative protein kinase C inhibitor

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular protein transport TAS
Traceable Author Statement
more info
 PubMed 
involved_in vesicle budding from membrane TAS
Traceable Author Statement
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016701.1 

    Range
    101..675
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    93430947..93431521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_022192.1: Suppressed sequence

    Description
    NM_022192.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.