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itga10 integrin, alpha 10 [ Danio rerio (zebrafish) ]

Gene ID: 572348, updated on 27-Mar-2024

Summary

Official Symbol
itga10provided by ZNC
Official Full Name
integrin, alpha 10provided by ZNC
Primary source
ZFIN:ZDB-GENE-100922-54
See related
Ensembl:ENSDARG00000002507 AllianceGenome:ZFIN:ZDB-GENE-100922-54
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-237p10.1
Summary
Predicted to enable metal ion binding activity. Predicted to act upstream of or within cell adhesion and integrin-mediated signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of integrin complex. Orthologous to human ITGA10 (integrin subunit alpha 10). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 16
Exon count:
31
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (14280493..14353827, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (14390373..14463707, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene glucosylceramidase beta 1 Neighboring gene ring finger protein 115a Neighboring gene polymerase (RNA) III (DNA directed) polypeptide C Neighboring gene cellular retinoic acid binding protein 2, a Neighboring gene uncharacterized LOC110437975

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables integrin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in cell adhesion mediated by integrin IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell-matrix adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in integrin-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of integrin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    14280493..14353827 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005157916.2XP_005157973.1  integrin alpha-10

    See identical proteins and their annotated locations for XP_005157973.1

    UniProtKB/TrEMBL
    A0A8M1RMK2
    Related
    ENSDARP00000013715.8, ENSDART00000011224.10
    Conserved Domains (3) summary
    smart00191
    Location:543597
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:164344
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6401056
    Integrin_alpha2; Integrin alpha
  2. XM_003200156.4XP_003200204.1  integrin alpha-10

    See identical proteins and their annotated locations for XP_003200204.1

    UniProtKB/TrEMBL
    A0A8M1RMK2
    Related
    ENSDARP00000120150.1, ENSDART00000139859.3
    Conserved Domains (3) summary
    smart00191
    Location:543597
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:164344
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6401056
    Integrin_alpha2; Integrin alpha