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fgf20b fibroblast growth factor 20b [ Danio rerio (zebrafish) ]

Gene ID: 564770, updated on 11-Apr-2024

Summary

Official Symbol
fgf20bprovided by ZNC
Official Full Name
fibroblast growth factor 20bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060117-5
See related
Ensembl:ENSDARG00000086070 AllianceGenome:ZFIN:ZDB-GENE-060117-5
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable fibroblast growth factor receptor binding activity and growth factor activity. Acts upstream of or within embryonic viscerocranium morphogenesis. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in cranial neural crest; kidney; and pharyngeal arch. Human ortholog(s) of this gene implicated in renal agenesis. Orthologous to human FGF20 (fibroblast growth factor 20). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 14
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (30491890..30493089)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (30151576..30152775)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 2 Neighboring gene mitochondrial calcium uptake family, member 3b Neighboring gene hairy-related 11 Neighboring gene hairy-related 5

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables fibroblast growth factor receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables growth factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within embryonic viscerocranium morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in fibroblast growth factor receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of cell population proliferation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
fibroblast growth factor 20b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039172.1NP_001034261.1  fibroblast growth factor 20b

    See identical proteins and their annotated locations for NP_001034261.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ241822
    UniProtKB/TrEMBL
    A0A8M1N872, Q2LJ24
    Related
    ENSDARP00000106996.1, ENSDART00000131174.3
    Conserved Domains (1) summary
    smart00442
    Location:60190
    FGF; Acidic and basic fibroblast growth factor family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    30491890..30493089
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)