U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

map3k8 mitogen-activated protein kinase kinase kinase 8 [ Danio rerio (zebrafish) ]

Gene ID: 563727, updated on 27-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
map3k8provided by ZNC
Official Full Name
mitogen-activated protein kinase kinase kinase 8provided by ZNC
Primary source
ZFIN:ZDB-GENE-100316-8
See related
Ensembl:ENSDARG00000061710 AllianceGenome:ZFIN:ZDB-GENE-100316-8
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable ATP binding activity and MAP kinase kinase kinase activity. Predicted to act upstream of or within protein phosphorylation. Orthologous to human MAP3K8 (mitogen-activated protein kinase kinase kinase 8). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See map3k8 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (23646981..23659536, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (23526372..23537763, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103911922 Neighboring gene uncharacterized LOC108191717 Neighboring gene mitochondrial poly(A) polymerase Neighboring gene junctional cadherin 5 associated a

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Molecular insight into regulation of miRNAs in the spleen of zebrafish (Danio rerio) upon pathogenic Streptococcus parauberis infection. Liyanage TD, et al. Fish Shellfish Immunol, 2020 Nov. PMID 32889099
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
mitogen-activated protein kinase kinase kinase 8

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    23646981..23659536 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021480321.1 → XP_021335996.1  mitogen-activated protein kinase kinase kinase 8

    UniProtKB/TrEMBL
    A0A8N7T7L4, E7F4L2
    Related
    ENSDARP00000082752.4, ENSDART00000088319.6
    Conserved Domains (1) summary
    cl21453
    Location:140 → 395
    PKc_like; Protein Kinases, catalytic domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394842.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    14362..26917 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_687085.7 → XP_692177.3  mitogen-activated protein kinase kinase kinase 8

    UniProtKB/TrEMBL
    A0A8N7T7L4, E7F4L2
    Conserved Domains (1) summary
    cl21453
    Location:140 → 395
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous