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elk3 ETS transcription factor ELK3 [ Danio rerio (zebrafish) ]

Gene ID: 557074, updated on 11-Apr-2024

Summary

Official Symbol
elk3provided by ZNC
Official Full Name
ETS transcription factor ELK3provided by ZNC
Primary source
ZFIN:ZDB-GENE-030716-2
See related
Ensembl:ENSDARG00000018688 AllianceGenome:ZFIN:ZDB-GENE-030716-2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:198153; zgc:198183; si:dkey-201e17.1; si:ch211-172b12.2
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in vascular endothelium. Orthologous to human ELK3 (ETS transcription factor ELK3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 4
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (7677346..7714047)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (7658161..7705418)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108183364 Neighboring gene leukotriene A4 hydrolase Neighboring gene cyclin dependent kinase 17 Neighboring gene thiaminase I, tandem duplicate 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ETS domain-containing protein Elk-3
Names
ELK3, ETS-domain protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030108.1NP_001025279.1  ETS domain-containing protein Elk-3

    See identical proteins and their annotated locations for NP_001025279.1

    Status: PROVISIONAL

    Source sequence(s)
    BX510353
    UniProtKB/TrEMBL
    Q5RHN6
    Related
    ENSDARP00000015956.7, ENSDART00000009909.9
    Conserved Domains (1) summary
    smart00413
    Location:1989
    ETS; erythroblast transformation specific domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    7677346..7714047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005164542.4XP_005164599.1  ETS domain-containing protein Elk-3 isoform X1

    See identical proteins and their annotated locations for XP_005164599.1

    UniProtKB/TrEMBL
    A0A8M2BBX3, F1QIB0
    Related
    ENSDARP00000123783.1, ENSDART00000149218.2
    Conserved Domains (1) summary
    smart00413
    Location:1989
    ETS; erythroblast transformation specific domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394548.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    259508..273601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)