pdk1 pyruvate dehydrogenase kinase, isozyme 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pdk1provided by ZNC
Official Full Name: pyruvate dehydrogenase kinase, isozyme 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-091204-402
See related: Ensembl:ENSDARG00000013128 AllianceGenome:ZFIN:ZDB-GENE-091204-402
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:zfos-979f1.3
Summary: Predicted to enable pyruvate dehydrogenase (acetyl-transferring) kinase activity. Predicted to be involved in protein phosphorylation and regulation of glucose metabolic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in brain. Orthologous to human PDK1 (pyruvate dehydrogenase kinase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (3131365..3149983, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (3125345..3144028, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables pyruvate dehydrogenase (acetyl-transferring) kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in protein phosphorylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of glucose metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

Preferred Names: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial

XP_683576.2

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The following sections contain reference sequences that belong to a specific genome build. Explain