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fdps farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) [ Danio rerio (zebrafish) ]

Gene ID: 552997, updated on 7-Apr-2024

Summary

Official Symbol
fdpsprovided by ZNC
Official Full Name
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)provided by ZNC
Primary source
ZFIN:ZDB-GENE-050506-78
See related
Ensembl:ENSDARG00000040890 AllianceGenome:ZFIN:ZDB-GENE-050506-78
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb23g06; im:6904202; wu:fb23g06
Summary
Predicted to enable dimethylallyltranstransferase activity and geranyltranstransferase activity. Predicted to be involved in farnesyl diphosphate biosynthetic process. Predicted to act upstream of or within isoprenoid biosynthetic process. Predicted to be active in cytoplasm. Is expressed in liver and yolk syncytial layer. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human FDPS (farnesyl diphosphate synthase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See fdps in Genome Data Viewer
Location:
chromosome: 16
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (14010173..14022911)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (14120053..14132791)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene si:dkey-85k15.6 Neighboring gene uncharacterized LOC100149015 Neighboring gene RUN and SH3 domain containing 1 Neighboring gene tripartite motif containing 109

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC114048

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables dimethylallyltranstransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables geranyltranstransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity, transferring alkyl or aryl (other than methyl) groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in farnesyl diphosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within isoprenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
farnesyl pyrophosphate synthase
NP_001020642.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025471.1NP_001020642.1  farnesyl pyrophosphate synthase

    See identical proteins and their annotated locations for NP_001020642.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097112
    UniProtKB/TrEMBL
    Q4V916
    Related
    ENSDARP00000111961.2, ENSDART00000122272.4
    Conserved Domains (1) summary
    pfam00348
    Location:53314
    polyprenyl_synt; Polyprenyl synthetase

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    14010173..14022911
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)