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mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) [ Danio rerio (zebrafish) ]

Gene ID: 550434, updated on 27-Mar-2024

Summary

Official Symbol
mad2l1provided by ZNC
Official Full Name
MAD2 mitotic arrest deficient-like 1 (yeast)provided by ZNC
Primary source
ZFIN:ZDB-GENE-030515-3
See related
Ensembl:ENSDARG00000004713 AllianceGenome:ZFIN:ZDB-GENE-030515-3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb408; zgc:112133
Summary
Predicted to be involved in mitotic spindle assembly checkpoint signaling. Predicted to be active in cytoplasm; kinetochore; and nucleoplasm. Is expressed in several structures, including immature eye; nervous system; neural tube; otic vesicle; and proliferative region. Orthologous to human MAD2L1 (mitotic arrest deficient 2 like 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See mad2l1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (57629370..57637769, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (57326930..57335329, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene dopamine receptor D4b Neighboring gene sirtuin 3 Neighboring gene phosphodiesterase 5A, cGMP-specific, b Neighboring gene arylsulfatase family, member J Neighboring gene calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in mitotic spindle assembly checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
mitotic spindle assembly checkpoint protein MAD2A
Names
spindle assembly checkpoint protein Mad2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017739.1NP_001017739.1  mitotic spindle assembly checkpoint protein MAD2A

    See identical proteins and their annotated locations for NP_001017739.1

    Status: PROVISIONAL

    Source sequence(s)
    BC093212
    UniProtKB/TrEMBL
    Q567E0
    Related
    ENSDARP00000003616.6, ENSDART00000028017.7
    Conserved Domains (1) summary
    pfam02301
    Location:10188
    HORMA; HORMA domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    57629370..57637769 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)