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ndufc2 NADH:ubiquinone oxidoreductase subunit C2 [ Danio rerio (zebrafish) ]

Gene ID: 541390, updated on 27-Mar-2024

Summary

Official Symbol
ndufc2provided by ZNC
Official Full Name
NADH:ubiquinone oxidoreductase subunit C2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050320-87
See related
Ensembl:ENSDARG00000102115 AllianceGenome:ZFIN:ZDB-GENE-050320-87
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:110155
Summary
Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to act upstream of or within mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Orthologous to human NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 15
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (11427622..11443217)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (11505227..11520822)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene RAB30, member RAS oncogene family Neighboring gene si:ch73-321d9.2 Neighboring gene uncharacterized LOC101885330 Neighboring gene solute carrier family 1 member 5

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within mitochondrial electron transport, NADH to ubiquinone IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in respirasome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] 1 subunit C2
Names
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
NP_001013535.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013517.1NP_001013535.1  NADH dehydrogenase [ubiquinone] 1 subunit C2

    See identical proteins and their annotated locations for NP_001013535.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091447
    UniProtKB/TrEMBL
    Q5BJK4
    Related
    ENSDARP00000141007.1, ENSDART00000168688.2
    Conserved Domains (1) summary
    pfam06374
    Location:4110
    NDUF_C2; NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    11427622..11443217
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)