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mat2b methionine adenosyltransferase 2 non-catalytic beta subunit methionine [ Danio rerio (zebrafish) ]

Gene ID: 541347, updated on 27-Mar-2024

Summary

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Official Symbol
mat2bprovided by ZNC
Official Full Name
methionine adenosyltransferase 2 non-catalytic beta subunit methionineprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-786
See related
Ensembl:ENSDARG00000012932 AllianceGenome:ZFIN:ZDB-GENE-030131-786
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc55d01; wu:fb48h02; wu:fc55d01; zgc:110308
Summary
Predicted to enable methionine adenosyltransferase regulator activity. Predicted to be involved in S-adenosylmethionine biosynthetic process. Predicted to act upstream of or within one-carbon metabolic process. Predicted to be part of methionine adenosyltransferase complex. Is expressed in anterior neural tube and optic cup. Orthologous to human MAT2B (methionine adenosyltransferase 2B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (32065304..32082130, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (32032046..32048872, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene zgc:165573 Neighboring gene si:ch211-160j14.2 Neighboring gene uncharacterized LOC100333843 Neighboring gene transfer RNA valine (anticodon AAC) Neighboring gene transfer RNA valine (anticodon CAC)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Embryo Microinjection of Selenomethionine Reduces Hatchability and Modifies Oxidant Responsive Gene Expression in Zebrafish. Thomas JK, et al. Sci Rep, 2016 May 23. PMID 27210033, Free PMC Article
  2. Disruption of the folate pathway in zebrafish causes developmental defects. Lee MS, et al. BMC Dev Biol, 2012 Apr 5. PMID 22480165, Free PMC Article
  3. A comparative map of the zebrafish genome. Woods IG, et al. Genome Res, 2000 Dec. PMID 11116086, Free PMC Article
  4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables methionine adenosyltransferase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in S-adenosylmethionine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in S-adenosylmethionine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within one-carbon metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of methionine adenosyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
methionine adenosyltransferase 2 subunit beta
Names
MAT II beta
methionine adenosyltransferase II, beta
NP_001013492.2
XP_005161452.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013474.2 → NP_001013492.2  methionine adenosyltransferase 2 subunit beta

    Status: VALIDATED

    Source sequence(s)
    EB966609, EH549300, EH566280, EH580990
    UniProtKB/Swiss-Prot
    Q5BJJ6
    UniProtKB/TrEMBL
    A0A8M1N4G7, F1RDD5
    Related
    ENSDARP00000016566.6, ENSDART00000003978.9
    Conserved Domains (2) summary
    cd05254
    Location:19 → 305
    dTDP_HR_like_SDR_e; dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs
    pfam04321
    Location:20 → 311
    RmlD_sub_bind; RmlD substrate binding domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    32065304..32082130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005161395.4 → XP_005161452.1  methionine adenosyltransferase 2 subunit beta isoform X1

    UniProtKB/Swiss-Prot
    Q5BJJ6
    UniProtKB/TrEMBL
    A0A8M2B8C1, E9QCP2
    Related
    ENSDARP00000123222.1, ENSDART00000135659.2
    Conserved Domains (2) summary
    cd05254
    Location:30 → 316
    dTDP_HR_like_SDR_e; dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs
    pfam04321
    Location:31 → 322
    RmlD_sub_bind; RmlD substrate binding domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5BJJ6.1 GenPept UniProtKB/Swiss-Prot:Q5BJJ6

Gene LinkOut

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