U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

BRAF B-Raf proto-oncogene, serine/threonine kinase [ Bos taurus (cattle) ]

Gene ID: 536051, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
BRAFprovided by VGNC
Official Full Name
B-Raf proto-oncogene, serine/threonine kinaseprovided by VGNC
Primary source
VGNC:VGNC:26551
See related
BGD:BT25565; Ensembl:ENSBTAG00000021761
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 4
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (104016173..104194462, complement)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104972256 Neighboring gene uncharacterized LOC132345136 Neighboring gene aarF domain containing kinase 2 Neighboring gene NADH:ubiquinone oxidoreductase subunit B2 Neighboring gene 5S ribosomal RNA Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene uncharacterized LOC101907501 Neighboring gene mitochondrial ribosomal protein S33

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
serine/threonine-protein kinase B-raf
XP_005205968.1
XP_005205973.1
XP_005205974.1
XP_005205975.1
XP_024846954.1
XP_024846956.1
XP_024846957.1
XP_059741940.1
XP_059741941.1
XP_059741942.1
XP_059741943.1
XP_059741944.1
XP_059741945.1
XP_059741946.1
XP_059741947.1
XP_059741948.1
XP_059741949.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    104016173..104194462 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059885960.1 → XP_059741943.1  serine/threonine-protein kinase B-raf isoform X4

  2. XM_059885958.1 → XP_059741941.1  serine/threonine-protein kinase B-raf isoform X2

    Related
    ENSBTAP00000090920.1, ENSBTAT00000129444.1

  3. XM_059885957.1 → XP_059741940.1  serine/threonine-protein kinase B-raf isoform X1

  4. XM_059885959.1 → XP_059741942.1  serine/threonine-protein kinase B-raf isoform X3

  5. XM_059885961.1 → XP_059741944.1  serine/threonine-protein kinase B-raf isoform X5

  6. XM_005205911.5 → XP_005205968.1  serine/threonine-protein kinase B-raf isoform X9

    See identical proteins and their annotated locations for XP_005205968.1

    UniProtKB/TrEMBL
    A0A3Q1M353
    Related
    ENSBTAP00000086663.1, ENSBTAT00000124680.1
    Conserved Domains (4) summary
    cd01816
    Location:155 → 226
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:462 → 714
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00069
    Location:457 → 712
    Pkinase; Protein kinase domain
    pfam00130
    Location:234 → 279
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  7. XM_024991189.2 → XP_024846957.1  serine/threonine-protein kinase B-raf isoform X8

    Related
    ENSBTAP00000088001.1, ENSBTAT00000126916.1
    Conserved Domains (3) summary
    cd01816
    Location:155 → 226
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:462 → 709
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:234 → 279
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  8. XM_024991188.2 → XP_024846956.1  serine/threonine-protein kinase B-raf isoform X7

    Related
    ENSBTAP00000091205.1, ENSBTAT00000113360.1
    Conserved Domains (3) summary
    cd01816
    Location:155 → 226
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:462 → 709
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:234 → 279
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  9. XM_059885966.1 → XP_059741949.1  serine/threonine-protein kinase B-raf isoform X16

    Related
    ENSBTAP00000086889.1, ENSBTAT00000116466.1

  10. XM_024991186.2 → XP_024846954.1  serine/threonine-protein kinase B-raf isoform X6

    Conserved Domains (3) summary
    cd01816
    Location:155 → 226
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:462 → 709
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:234 → 279
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  11. XM_059885965.1 → XP_059741948.1  serine/threonine-protein kinase B-raf isoform X13

    Related
    ENSBTAP00000029006.7, ENSBTAT00000029006.7

  12. XM_059885963.1 → XP_059741946.1  serine/threonine-protein kinase B-raf isoform X11

  13. XM_059885962.1 → XP_059741945.1  serine/threonine-protein kinase B-raf isoform X10

  14. XM_059885964.1 → XP_059741947.1  serine/threonine-protein kinase B-raf isoform X12

    Related
    ENSBTAP00000057958.2, ENSBTAT00000068933.2

  15. XM_005205916.5 → XP_005205973.1  serine/threonine-protein kinase B-raf isoform X14

    See identical proteins and their annotated locations for XP_005205973.1

    UniProtKB/TrEMBL
    A0A3Q1LML5
    Conserved Domains (4) summary
    cd01816
    Location:155 → 226
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:462 → 665
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:234 → 279
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam07714
    Location:456 → 662
    Pkinase_Tyr; Protein tyrosine kinase

  16. XM_005205918.3 → XP_005205975.1  serine/threonine-protein kinase B-raf isoform X15

    UniProtKB/TrEMBL
    A0A3Q1LML5
    Conserved Domains (4) summary
    cd01816
    Location:155 → 226
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:462 → 663
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:234 → 279
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam07714
    Location:456 → 662
    Pkinase_Tyr; Protein tyrosine kinase

  17. XM_005205917.5 → XP_005205974.1  serine/threonine-protein kinase B-raf isoform X14

    See identical proteins and their annotated locations for XP_005205974.1

    UniProtKB/TrEMBL
    A0A3Q1LML5
    Related
    ENSBTAP00000064502.2, ENSBTAT00000086962.2
    Conserved Domains (4) summary
    cd01816
    Location:155 → 226
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:462 → 665
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:234 → 279
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam07714
    Location:456 → 662
    Pkinase_Tyr; Protein tyrosine kinase
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.