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ADCY3 adenylate cyclase 3 [ Bos taurus (cattle) ]

Gene ID: 535603, updated on 3-Apr-2024

Summary

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Official Symbol
ADCY3provided by VGNC
Official Full Name
adenylate cyclase 3provided by VGNC
Primary source
VGNC:VGNC:25644
See related
BGD:BT17942; Ensembl:ENSBTAG00000018705
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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Genomic context

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See ADCY3 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (74334641..74418321)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene EFR3 homolog B Neighboring gene DnaJ heat shock protein family (Hsp40) member C27 Neighboring gene translation initiation factor IF-2 Neighboring gene centromere protein O Neighboring gene peptidyl-tRNA hydrolase domain containing 1 Neighboring gene nuclear receptor coactivator 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Catalytic Mechanism of Mammalian Adenylyl Cyclase: A Computational Investigation. Hahn DK, et al. Biochemistry, 2015 Oct 13. PMID 26393535, Free PMC Article
  2. Distinct mechanisms of regulation by Ca2+/calmodulin of type 1 and 8 adenylyl cyclases support their different physiological roles. Masada N, et al. J Biol Chem, 2009 Feb 13. PMID 19029295, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables adenylate cyclase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cAMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adenylate cyclase type 3
Names
adenylate cyclase 8 (brain)
NP_001193013.1
XP_005213076.1
XP_059747333.1
XP_059747334.1
XP_059747335.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206084.1 → NP_001193013.1  adenylate cyclase type 3

    See identical proteins and their annotated locations for NP_001193013.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000011
    UniProtKB/TrEMBL
    A0A3Q1MKX5, F1MPC9
    Conserved Domains (3) summary
    smart00044
    Location:884 → 1102
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    pfam00211
    Location:915 → 1122
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:2 → 303
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    74334641..74418321
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005213019.5 → XP_005213076.1  adenylate cyclase type 3 isoform X1

    See identical proteins and their annotated locations for XP_005213076.1

    UniProtKB/TrEMBL
    A0A3Q1MKX5, F1MPC9
    Related
    ENSBTAP00000032877.5, ENSBTAT00000032950.5
    Conserved Domains (3) summary
    smart00044
    Location:884 → 1102
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    pfam00211
    Location:915 → 1122
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:2 → 303
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

  2. XM_059891351.1 → XP_059747334.1  adenylate cyclase type 3 isoform X2

  3. XM_059891350.1 → XP_059747333.1  adenylate cyclase type 3 isoform X1

    UniProtKB/TrEMBL
    F1MPC9

  4. XM_059891352.1 → XP_059747335.1  adenylate cyclase type 3 isoform X3

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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