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PLA2G6 phospholipase A2 group VI [ Bos taurus (cattle) ]

Gene ID: 535381, updated on 5-Mar-2024

Summary

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Official Symbol
PLA2G6provided by VGNC
Official Full Name
phospholipase A2 group VIprovided by VGNC
Primary source
VGNC:VGNC:32964
See related
BGD:BT20707; Ensembl:ENSBTAG00000014015
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (109891823..109950622, complement)

Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 16 member 8 Neighboring gene BAR/IMD domain containing adaptor protein 2 like 2 Neighboring gene MAF bZIP transcription factor F Neighboring gene transmembrane protein 184B

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium-independent phospholipase A2 activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cardiolipin acyl-chain remodeling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
85/88 kDa calcium-independent phospholipase A2
Names
phospholipase A2, group VI (cytosolic, calcium-independent)
XP_002687969.2
XP_005207423.1
XP_005207424.1
XP_010804037.1
XP_015326871.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    109891823..109950622 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010805735.4 → XP_010804037.1  85/88 kDa calcium-independent phospholipase A2 isoform X4

    See identical proteins and their annotated locations for XP_010804037.1

    UniProtKB/TrEMBL
    A0A3Q1M361
    Related
    ENSBTAP00000099206.1, ENSBTAT00000117756.1
    Conserved Domains (5) summary
    cd07212
    Location:459 → 772
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    cd00204
    Location:187 → 313
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:197 → 289
    Ank_2; Ankyrin repeats (3 copies)
    pfam13857
    Location:312 → 370
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:192 → 224
    ANK; ANK repeat [structural motif]

  2. XM_015471385.3 → XP_015326871.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1M361
    Conserved Domains (4) summary
    cd07212
    Location:479 → 792
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    cd00204
    Location:285 → 403
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:291 → 380
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]

  3. XM_005207367.5 → XP_005207424.1  85/88 kDa calcium-independent phospholipase A2 isoform X3

    See identical proteins and their annotated locations for XP_005207424.1

    UniProtKB/TrEMBL
    A0A3Q1LN87, A0A3Q1M361
    Related
    ENSBTAP00000058418.1, ENSBTAT00000067616.2
    Conserved Domains (4) summary
    cd07212
    Location:467 → 780
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    cd00204
    Location:326 → 433
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:332 → 421
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:327 → 355
    ANK; ANK repeat [structural motif]

  4. XM_002687923.7 → XP_002687969.2  85/88 kDa calcium-independent phospholipase A2 isoform X1

    See identical proteins and their annotated locations for XP_002687969.2

    UniProtKB/TrEMBL
    A0A3Q1M361, E1BB89
    Related
    ENSBTAP00000092052.1, ENSBTAT00000118432.1
    Conserved Domains (4) summary
    cd07212
    Location:520 → 833
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    cd00204
    Location:326 → 444
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:332 → 421
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:327 → 355
    ANK; ANK repeat [structural motif]

  5. XM_005207366.5 → XP_005207423.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

    See identical proteins and their annotated locations for XP_005207423.1

    UniProtKB/TrEMBL
    A0A3Q1M361
    Related
    ENSBTAP00000082278.1, ENSBTAT00000115735.1
    Conserved Domains (4) summary
    cd07212
    Location:479 → 792
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    cd00204
    Location:285 → 403
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:291 → 380
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
Nucleotide Protein Strain
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