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ADCY8 adenylate cyclase 8 [ Bos taurus (cattle) ]

Gene ID: 535017, updated on 5-Mar-2024

Summary

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Official Symbol
ADCY8provided by VGNC
Official Full Name
adenylate cyclase 8provided by VGNC
Primary source
VGNC:VGNC:25649
See related
BGD:BT15209; Ensembl:ENSBTAG00000014600
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (9754131..9979386)

Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112449572 Neighboring gene nucleophosmin-like Neighboring gene small ribosomal subunit protein eS25-like Neighboring gene ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 Neighboring gene uncharacterized LOC132342179

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural insights into calmodulin/adenylyl cyclase 8 interaction. Herbst S, et al. Anal Bioanal Chem, 2013 Nov. PMID 24071896
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables adenylate cyclase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cAMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adenylate cyclase type 8
NP_001179770.1
XP_010810239.2
XP_024857408.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192841.1 → NP_001179770.1  adenylate cyclase type 8

    See identical proteins and their annotated locations for NP_001179770.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000014
    UniProtKB/TrEMBL
    E1BQ12
    Related
    ENSBTAP00000019434.5, ENSBTAT00000019434.7
    Conserved Domains (3) summary
    pfam00211
    Location:975 → 1174
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam06327
    Location:619 → 713
    DUF1053; Domain of Unknown Function (DUF1053)
    pfam16214
    Location:163 → 402
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    9754131..9979386
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010811937.4 → XP_010810239.2  adenylate cyclase type 8 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LYZ1
    Related
    ENSBTAP00000060884.1, ENSBTAT00000067819.2
    Conserved Domains (3) summary
    pfam00211
    Location:945 → 1144
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam06327
    Location:619 → 713
    DUF1053; Domain of Unknown Function (DUF1053)
    pfam16214
    Location:163 → 402
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

  2. XM_025001640.2 → XP_024857408.1  adenylate cyclase type 8 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LRN0
    Related
    ENSBTAP00000059662.1, ENSBTAT00000070964.2
    Conserved Domains (2) summary
    pfam00211
    Location:909 → 1108
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam16214
    Location:163 → 402
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
Nucleotide Protein Strain
Heading Accession and Version

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