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Pla2g6 phospholipase A2, group VI [ Mus musculus (house mouse) ]

Gene ID: 53357, updated on 21-Apr-2024

Summary

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Official Symbol
Pla2g6provided by MGI
Official Full Name
phospholipase A2, group VIprovided by MGI
Primary source
MGI:MGI:1859152
See related
Ensembl:ENSMUSG00000042632 AllianceGenome:MGI:1859152
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
iPLA2; PNPLA9; iPLA2beta; iPLA(2)beta
Summary
Enables calcium-independent phospholipase A2 activity; palmitoyl-CoA hydrolase activity; and serine hydrolase activity. Involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in centriolar satellite; cytosol; and extracellular space. Predicted to be active in mitochondrion. Is expressed in 1st branchial arch maxillary component; olfactory placode; otic pit; and trunk somite. Used to study neurodegeneration with brain iron accumulation 2a. Human ortholog(s) of this gene implicated in dystonia 12; neuroaxonal dystrophy; and neurodegenerative disease (multiple). Orthologous to human PLA2G6 (phospholipase A2 group VI). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 76.7), adrenal adult (RPKM 14.0) and 23 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 E1; 15 37.7 cM
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (79170428..79212915, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (79286228..79328385, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene lectin, galactose binding, soluble 1, pseudogene 2 Neighboring gene BAI1-associated protein 2-like 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:79110794-79110903 Neighboring gene predicted gene, 41358 Neighboring gene STARR-positive B cell enhancer ABC_E7389 Neighboring gene predicted gene 20420 Neighboring gene STARR-positive B cell enhancer ABC_E1913 Neighboring gene STARR-seq mESC enhancer starr_39174 Neighboring gene v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) Neighboring gene transmembrane protein 184b Neighboring gene microRNA 1943

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. iPLA2β-Null Mice Show HCC Protection by an Induction of Cell-Cycle Arrest after Diethylnitrosamine Treatment. Andrade A, et al. Int J Mol Sci, 2022 Nov 9. PMID 36430237, Free PMC Article
  2. Myeloid- and hepatocyte-specific deletion of group VIA calcium-independent phospholipase A2 leads to dichotomous opposing phenotypes during MCD diet-induced NASH. Jansakun C, et al. Biochim Biophys Acta Mol Basis Dis, 2023 Jan 1. PMID 36334837
  3. Acidic Calcium-Independent Phospholipase A2 Regulates Eosinophil-Mediated Pathology during Filarial Manifestation of Tropical Pulmonary Eosinophilia. Sharma P, et al. J Immunol, 2021 Feb 15. PMID 33441441
  4. Rescue of Hepatic Phospholipid Remodeling Defectin iPLA2β-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver. Chamulitrat W, et al. Biomolecules, 2020 Sep 17. PMID 32957701, Free PMC Article
  5. Loss of tyrosine hydroxylase, motor deficits and elevated iron in a mouse model of phospholipase A2G6-associated neurodegeneration (PLAN). Minkley M, et al. Brain Res, 2020 Dec 1. PMID 32818532

See all (117) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Myeloid-specific deletion of group VIA calcium-independent phospholipase A2 induces pro-inflammatory LPS response predominantly in male mice via MIP-1alpha activation.
    Title: Myeloid-specific deletion of group VIA calcium-independent phospholipase A2 induces pro-inflammatory LPS response predominantly in male mice via MIP-1α activation.
  2. PLA2G6 mutations cause motor dysfunction phenotypes of young-onset dystonia-parkinsonism type 14 and can be relieved by DHA treatment in animal models.
    Title: PLA2G6 mutations cause motor dysfunction phenotypes of young-onset dystonia-parkinsonism type 14 and can be relieved by DHA treatment in animal models.
  3. iPLA2beta Contributes to ER Stress-Induced Apoptosis during Myocardial Ischemia/Reperfusion Injury.
    Title: iPLA(2)β Contributes to ER Stress-Induced Apoptosis during Myocardial Ischemia/Reperfusion Injury.
  4. Rescue of Hepatic Phospholipid Remodeling Defectin iPLA2beta-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver.
    Title: Rescue of Hepatic Phospholipid Remodeling Defectin iPLA2β-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver.
  5. Acidic Calcium-Independent Phospholipase A2 Regulates Eosinophil-Mediated Pathology during Filarial Manifestation of Tropical Pulmonary Eosinophilia.
    Title: Acidic Calcium-Independent Phospholipase A2 Regulates Eosinophil-Mediated Pathology during Filarial Manifestation of Tropical Pulmonary Eosinophilia.
  6. iPLA2beta-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4.
    Title: iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4.
  7. Metabolic Effects of Selective Deletion of Group VIA Phospholipase A2 from Macrophages or Pancreatic Islet Beta-Cells.
    Title: Metabolic Effects of Selective Deletion of Group VIA Phospholipase A(2) from Macrophages or Pancreatic Islet Beta-Cells.
  8. Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages.
    Title: Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages.
  9. This study provides insights into iPla2b (PLA2G6) inactivation for injury susceptibility under normal conditions and liver fibrosis and cholangiopathies during methionine-choline-deficient diet feeding.
    Title: iPla2β Deficiency Suppresses Hepatic ER UPR, Fxr, and Phospholipids in Mice Fed with MCD Diet, Resulting in Exacerbated Hepatic Bile Acids and Biliary Cell Proliferation.
  10. the regulation of iPLA2beta/Cardiolipin/Opa1 by HGSD may prevent beta-cell apoptosis and may improve islet beta-cell function in Type 2 diabetic mice and in palmitate-treated MIN6 cells
    Title: Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA(2)β/Cardiolipin/Opa1 pathway in db/db mice and in Palmitate-treated MIN6 β-cells.
Submit: New GeneRIF Correction See all GeneRIFs (73)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Spontaneous (1)  1 citation
  • Targeted (7)  1 citation
  • Chemically induced (ENU) (1) 
  • Endonuclease-mediated (4) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP-dependent protein binding ISO
Inferred from Sequence Orthology
more info
  
enables calcium-independent phospholipase A2 activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium-independent phospholipase A2 activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables calcium-independent phospholipase A2 activity ISO
Inferred from Sequence Orthology
more info
  
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables long-chain fatty acyl-CoA hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables long-chain fatty acyl-CoA hydrolase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables long-chain fatty acyl-CoA hydrolase activity ISO
Inferred from Sequence Orthology
more info
  
enables lysophospholipase activity ISO
Inferred from Sequence Orthology
more info
  
enables phosphatidyl phospholipase B activity IEA
Inferred from Electronic Annotation
more info
  
enables phospholipase A2 activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
  
enables serine hydrolase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in antibacterial humoral response ISO
Inferred from Sequence Orthology
more info
  
involved_in cardiolipin acyl-chain remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cardiolipin acyl-chain remodeling ISO
Inferred from Sequence Orthology
more info
  
involved_in cardiolipin biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within chemotaxis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in memory ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of synaptic transmission, glutamatergic ISO
Inferred from Sequence Orthology
more info
  
involved_in phosphatidylcholine catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of arachidonic acid secretion ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of ceramide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of ceramide biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of exocytosis ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of insulin secretion involved in cellular response to glucose stimulus ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of protein kinase C signaling ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of release of cytochrome c from mitochondria ISO
Inferred from Sequence Orthology
more info
  
involved_in response to endoplasmic reticulum stress ISO
Inferred from Sequence Orthology
more info
  
involved_in urinary bladder smooth muscle contraction ISO
Inferred from Sequence Orthology
more info
  
involved_in vasodilation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
85/88 kDa calcium-independent phospholipase A2
Names
2-lysophosphatidylcholine acylhydrolase
85 kDa calcium-independent phospholipase A2
GVI PLA2
caI-PLA2
group VI phospholipase A2
iPLA2-beta
intracellular membrane-associated calcium-independent phospholipase A2 beta
palmitoyl-CoA hydrolase
patatin-like phospholipase domain-containing protein 9
NP_001185952.1
NP_001185953.1
NP_001185954.1
NP_001403319.1
NP_001403320.1
NP_001403321.1
NP_001403322.1
NP_001403324.1
NP_001403325.1
NP_001403326.1
NP_001403327.1
NP_001403328.1
NP_001403329.1
NP_001403333.1
NP_058611.1
XP_036015396.1
XP_036015397.1
XP_036015398.1
XP_036015399.1
XP_036015400.1
XP_036015401.1
XP_036015402.1
XP_036015403.1
XP_036015404.1
XP_036015405.1
XP_036015406.1
XP_036015407.1
XP_036015409.1
XP_036015410.1
XP_036015411.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199023.2 → NP_001185952.1  85/88 kDa calcium-independent phospholipase A2 isoform 2

    See identical proteins and their annotated locations for NP_001185952.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and has an additional in-frame exon in the coding region, compared to variant 1. It encodes a longer isoform (2) than isoform 1.
    Source sequence(s)
    AC165278, AL591913
    Consensus CDS
    CCDS56991.1
    UniProtKB/Swiss-Prot
    P97819, Q99LA9, Q9JK61
    UniProtKB/TrEMBL
    Q3U613, Q7TPX2
    Related
    ENSMUSP00000134672.2, ENSMUST00000174021.8
    Conserved Domains (5) summary
    cd07212
    Location:481 → 794
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 412
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 248
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  2. NM_001199024.2 → NP_001185953.1  85/88 kDa calcium-independent phospholipase A2 isoform 1

    See identical proteins and their annotated locations for NP_001185953.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1, and encodes isoform (1). Variants 1, 3, and 4 encode the same protein (isoform 1).
    Source sequence(s)
    AC165278, AL591913
    Consensus CDS
    CCDS27637.1
    UniProtKB/TrEMBL
    Q3U613, Q3UN31, Q7TPX2
    Related
    ENSMUSP00000132071.3, ENSMUST00000166977.9
    Conserved Domains (5) summary
    cd07212
    Location:426 → 739
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 390
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 248
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  3. NM_001199025.2 → NP_001185954.1  85/88 kDa calcium-independent phospholipase A2 isoform 1

    See identical proteins and their annotated locations for NP_001185954.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1, and encodes isoform (1). Variants 1, 3, and 4 encode the same protein (isoform 1).
    Source sequence(s)
    AC165278, AL591913
    Consensus CDS
    CCDS27637.1
    UniProtKB/TrEMBL
    Q3U613, Q3UN31, Q7TPX2
    Related
    ENSMUSP00000131081.3, ENSMUST00000172403.9
    Conserved Domains (5) summary
    cd07212
    Location:426 → 739
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 390
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 248
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  4. NM_001416390.1 → NP_001403319.1  85/88 kDa calcium-independent phospholipase A2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC165278, AL591913
    UniProtKB/TrEMBL
    Q3UN31

  5. NM_001416391.1 → NP_001403320.1  85/88 kDa calcium-independent phospholipase A2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC165278, AL591913
    UniProtKB/TrEMBL
    Q3UN31
    Related
    ENSMUSP00000134456.2, ENSMUST00000173163.8

  6. NM_001416392.1 → NP_001403321.1  85/88 kDa calcium-independent phospholipase A2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC165278, AL591913
    UniProtKB/TrEMBL
    Q3UN31

  7. NM_001416393.1 → NP_001403322.1  85/88 kDa calcium-independent phospholipase A2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC165278, AL591913
    UniProtKB/TrEMBL
    Q3UN31

  8. NM_001416395.1 → NP_001403324.1  85/88 kDa calcium-independent phospholipase A2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL591913
    UniProtKB/TrEMBL
    Q3UN31

  9. NM_001416396.1 → NP_001403325.1  85/88 kDa calcium-independent phospholipase A2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC165278, AL591913
    UniProtKB/Swiss-Prot
    P97819, Q99LA9, Q9JK61

  10. NM_001416397.1 → NP_001403326.1  85/88 kDa calcium-independent phospholipase A2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC165278, AL591913
    UniProtKB/Swiss-Prot
    P97819, Q99LA9, Q9JK61

  11. NM_001416398.1 → NP_001403327.1  85/88 kDa calcium-independent phospholipase A2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC165278, AL591913
    UniProtKB/Swiss-Prot
    P97819, Q99LA9, Q9JK61

  12. NM_001416399.1 → NP_001403328.1  85/88 kDa calcium-independent phospholipase A2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC165278, AL591913
    UniProtKB/Swiss-Prot
    P97819, Q99LA9, Q9JK61

  13. NM_001416400.1 → NP_001403329.1  85/88 kDa calcium-independent phospholipase A2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC165278, AL591913

  14. NM_001416404.1 → NP_001403333.1  85/88 kDa calcium-independent phospholipase A2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC165278, AL591913

  15. NM_016915.5 → NP_058611.1  85/88 kDa calcium-independent phospholipase A2 isoform 1

    See identical proteins and their annotated locations for NP_058611.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shortest transcript and encodes the shorter isoform (1). Variants 1, 3, and 4 encode the same protein (isoform 1).
    Source sequence(s)
    AC165278, AL591913
    Consensus CDS
    CCDS27637.1
    UniProtKB/TrEMBL
    Q3U613, Q3UN31, Q7TPX2
    Related
    ENSMUSP00000044234.9, ENSMUST00000047816.15
    Conserved Domains (5) summary
    cd07212
    Location:426 → 739
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 390
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 248
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

RNA

  1. NR_183841.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC165278, AL591913

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    79170428..79212915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159506.1 → XP_036015399.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

    Conserved Domains (5) summary
    cd07212
    Location:481 → 940
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 412
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_036159511.1 → XP_036015404.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

    Conserved Domains (5) summary
    cd07212
    Location:481 → 940
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 412
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_036159504.1 → XP_036015397.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

    Conserved Domains (5) summary
    cd07212
    Location:481 → 940
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 412
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_036159507.1 → XP_036015400.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

    Conserved Domains (5) summary
    cd07212
    Location:481 → 940
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 412
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  5. XM_036159514.1 → XP_036015407.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

    UniProtKB/TrEMBL
    Q3U613, Q7TPX2
    Conserved Domains (3) summary
    cd07212
    Location:426 → 885
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_036159512.1 → XP_036015405.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

    Conserved Domains (5) summary
    cd07212
    Location:481 → 940
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 412
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  7. XM_036159503.1 → XP_036015396.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

    Conserved Domains (5) summary
    cd07212
    Location:481 → 940
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 412
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  8. XM_036159505.1 → XP_036015398.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

    Conserved Domains (5) summary
    cd07212
    Location:481 → 940
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 412
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  9. XM_036159513.1 → XP_036015406.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

    UniProtKB/TrEMBL
    Q3U613, Q7TPX2
    Conserved Domains (3) summary
    cd07212
    Location:426 → 885
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)

  10. XM_036159517.1 → XP_036015410.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    Conserved Domains (1) summary
    cd07212
    Location:26 → 485
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

  11. XM_036159516.1 → XP_036015409.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

    UniProtKB/TrEMBL
    Q3U613, Q7TPX2
    Conserved Domains (3) summary
    cd07212
    Location:426 → 885
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)

  12. XM_036159508.1 → XP_036015401.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

    Conserved Domains (5) summary
    cd07212
    Location:481 → 940
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 412
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  13. XM_036159509.1 → XP_036015402.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

    Conserved Domains (5) summary
    cd07212
    Location:481 → 940
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 412
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  14. XM_036159510.1 → XP_036015403.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

    Conserved Domains (5) summary
    cd07212
    Location:481 → 940
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
    PHA02875
    Location:220 → 412
    PHA02875; ankyrin repeat protein; Provisional
    sd00045
    Location:286 → 314
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:156 → 249
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:103 → 183
    Ank_2; Ankyrin repeats (3 copies)

  15. XM_036159518.1 → XP_036015411.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

    Conserved Domains (1) summary
    cd07212
    Location:26 → 485
    Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9

RNA

  1. XR_004938853.1 RNA Sequence

  2. XR_003951405.1 RNA Sequence

  3. XR_004938855.1 RNA Sequence

  4. XR_004938854.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P97819.3 GenPept UniProtKB/Swiss-Prot:P97819

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