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MYLK2 myosin light chain kinase 2 [ Bos taurus (cattle) ]

Gene ID: 533378, updated on 3-Apr-2024

Summary

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Official Symbol
MYLK2provided by VGNC
Official Full Name
myosin light chain kinase 2provided by VGNC
Primary source
VGNC:VGNC:31806
See related
BGD:BT26657; Ensembl:ENSBTAG00000014930
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (61348622..61369691)

Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107133075 Neighboring gene BCL2 like 1 Neighboring gene TPX2 microtubule nucleation factor Neighboring gene uncharacterized LOC132346946 Neighboring gene interferon regulatory factor 4 Neighboring gene forkhead box S1 Neighboring gene dual specificity phosphatase 15

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC155182

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables myosin light chain kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myosin light chain kinase 2, skeletal/cardiac muscle
Names
MLCK2
myosin light chain kinase 2, skeletal muscle
NP_001077188.1
XP_005214824.1
XP_005214826.1
XP_010809800.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083719.1 → NP_001077188.1  myosin light chain kinase 2, skeletal/cardiac muscle

    See identical proteins and their annotated locations for NP_001077188.1

    Status: PROVISIONAL

    Source sequence(s)
    BC134664
    UniProtKB/Swiss-Prot
    A4IFM7
    Related
    ENSBTAP00000019875.4, ENSBTAT00000019875.5
    Conserved Domains (2) summary
    cd14190
    Location:308 → 567
    STKc_MLCK2; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 2
    cl28033
    Location:36 → 246
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    61348622..61369691
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005214769.5 → XP_005214826.1  myosin light chain kinase 2, skeletal/cardiac muscle isoform X1

    See identical proteins and their annotated locations for XP_005214826.1

    UniProtKB/Swiss-Prot
    A4IFM7
    Conserved Domains (2) summary
    cd14190
    Location:308 → 567
    STKc_MLCK2; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 2
    cl28033
    Location:36 → 246
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  2. XM_010811498.3 → XP_010809800.1  myosin light chain kinase 2, skeletal/cardiac muscle isoform X1

    See identical proteins and their annotated locations for XP_010809800.1

    UniProtKB/Swiss-Prot
    A4IFM7
    Conserved Domains (2) summary
    cd14190
    Location:308 → 567
    STKc_MLCK2; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 2
    cl28033
    Location:36 → 246
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  3. XM_005214767.5 → XP_005214824.1  myosin light chain kinase 2, skeletal/cardiac muscle isoform X1

    See identical proteins and their annotated locations for XP_005214824.1

    UniProtKB/Swiss-Prot
    A4IFM7
    Conserved Domains (2) summary
    cd14190
    Location:308 → 567
    STKc_MLCK2; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 2
    cl28033
    Location:36 → 246
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A4IFM7.1 GenPept UniProtKB/Swiss-Prot:A4IFM7

Gene LinkOut

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