NPR1 natriuretic peptide receptor 1 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: NPR1provided by VGNC
Official Full Name: natriuretic peptide receptor 1provided by VGNC
Primary source: VGNC:VGNC:32213
See related: Ensembl:ENSBTAG00000006234
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	3	NC_037330.1 (16686877..16700408, complement)

Chromosome 3 - NC_037330.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

MARC_5357-5358:996690315:1 (e-PCR)
- UniSTS:269492

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables guanylate cyclase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables peptide receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cGMP biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in receptor guanylyl cyclase signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: atrial natriuretic peptide receptor 1

Names: natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

NP_001179680.1

EC 4.6.1.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001192751.1 → NP_001179680.1 atrial natriuretic peptide receptor 1 precursor

See identical proteins and their annotated locations for NP_001179680.1

Status: PROVISIONAL

Source sequence(s)

NKLS02000003

UniProtKB/TrEMBL

E1BN71

Related

ENSBTAP00000008184.5, ENSBTAT00000008184.7

Conserved Domains (7) summary

PHA02988
Location:542 → 807

PHA02988; hypothetical protein; Provisional

smart00044
Location:843 → 1035

CYCc; Adenylyl- / guanylyl cyclase, catalytic domain

cd14042
Location:537 → 810

PK_GC-A_B; Pseudokinase domain of the membrane Guanylate Cyclase receptors, GC-A and GC-B

pfam00211
Location:870 → 1056

Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain

pfam01094
Location:57 → 419

ANF_receptor; Receptor family ligand binding region

pfam07701
Location:819 → 864

HNOBA; Heme NO binding associated

cl10011
Location:39 → 446

Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily