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CAMK2A calcium/calmodulin dependent protein kinase II alpha [ Bos taurus (cattle) ]

Gene ID: 530719, updated on 5-Mar-2024

Summary

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Official Symbol
CAMK2Aprovided by VGNC
Official Full Name
calcium/calmodulin dependent protein kinase II alphaprovided by VGNC
Primary source
VGNC:VGNC:26721
See related
BGD:BT15769; Ensembl:ENSBTAG00000020087
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See CAMK2A in Genome Data Viewer
Location:
chromosome: 7
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (61574371..61640194, complement)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene caudal type homeobox 1 Neighboring gene U1 spliceosomal RNA Neighboring gene solute carrier family 6 member 7 Neighboring gene arylsulfatase family member I Neighboring gene treacle ribosome biogenesis factor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. Aromolaran AS, et al. Am J Physiol Cell Physiol, 2007 Jul. PMID 17344311
  2. The small GTPase RAB28 is required for phagocytosis of cone outer segments by the murine retinal pigmented epithelium. Ying G, et al. J Biol Chem, 2018 Nov 9. PMID 30228185, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC139375, MGC155201

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calcium/calmodulin-dependent protein kinase type II subunit alpha
Names
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
calcium/calmodulin-dependent protein kinase type II alpha
NP_001069406.1
XP_005209650.1
XP_015327787.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075938.1 → NP_001069406.1  calcium/calmodulin-dependent protein kinase type II subunit alpha

    See identical proteins and their annotated locations for NP_001069406.1

    Status: PROVISIONAL

    Source sequence(s)
    BC123428
    UniProtKB/TrEMBL
    A0A3Q1LUJ3, F1N3S6, Q08E45
    Related
    ENSBTAP00000026762.5, ENSBTAT00000026762.6
    Conserved Domains (2) summary
    cd14086
    Location:11 → 302
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:346 → 473
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    61574371..61640194 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005209593.3 → XP_005209650.1  calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1

    See identical proteins and their annotated locations for XP_005209650.1

    UniProtKB/TrEMBL
    A0A3Q1LUJ3, A0A3Q1MKC7
    Related
    ENSBTAP00000071965.1, ENSBTAT00000073084.2
    Conserved Domains (2) summary
    cd14086
    Location:11 → 302
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:357 → 484
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  2. XM_015472301.2 → XP_015327787.1  calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LUJ3
    Related
    ENSBTAP00000060808.1, ENSBTAT00000066579.2
    Conserved Domains (2) summary
    cd14086
    Location:11 → 302
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:346 → 473
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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