PLA2G3 phospholipase A2 group III [Bos taurus (cattle)] - Gene

Summary

Official Symbol: PLA2G3provided by VGNC
Official Full Name: phospholipase A2 group IIIprovided by VGNC
Primary source: VGNC:VGNC:32959
See related: Ensembl:ENSBTAG00000011962
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	17	NC_037344.1 (69982739..69988677, complement)

Chromosome 17 - NC_037344.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables phospholipase A2 activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in arachidonic acid secretion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phospholipid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: group 3 secretory phospholipase A2

Names: GIII sPLA2; group III secretory phospholipase A2; phosphatidylcholine 2-acylhydrolase 3; phosphatidylcholine 2-acylhydrolase GIII; sPLA2-III

NP_001074379.2

EC 3.1.1.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080910.3 → NP_001074379.2 group 3 secretory phospholipase A2 precursor

Status: VALIDATED

Source sequence(s)

NKLS02000017

UniProtKB/TrEMBL

E1BEM2

Related

ENSBTAP00000015876.3, ENSBTAT00000015876.4

Conserved Domains (2) summary

cd04704
Location:151 → 247

PLA2_bee_venom_like; PLA2_bee_venom_like: A sub-family of Phospholipase A2, similar to bee venom PLA2. PLA2 is a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the ...

cl05417
Location:360 → 434

PLA2_like; PLA2_like: Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a ...