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CALCRL calcitonin receptor like receptor [ Bos taurus (cattle) ]

Gene ID: 527140, updated on 5-Mar-2024

Summary

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Official Symbol
CALCRLprovided by VGNC
Official Full Name
calcitonin receptor like receptorprovided by VGNC
Primary source
VGNC:VGNC:26705
See related
BGD:BT29805; Ensembl:ENSBTAG00000008483
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (8891723..9020443)

Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132342941 Neighboring gene peptidylprolyl isomerase-like 1 pseudogene Neighboring gene tissue factor pathway inhibitor Neighboring gene uncharacterized LOC132342942 Neighboring gene zinc finger SWIM-type containing 2 Neighboring gene family with sequence similarity 171 member B

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Temporo-spatial expression of adrenomedullin and its receptors in the bovine placenta. Hayashi KG, et al. Reprod Biol Endocrinol, 2013 Jul 13. PMID 23849271, Free PMC Article
  2. Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking. Bomberger JM, et al. J Biol Chem, 2005 Mar 11. PMID 15613468
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC155061

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables adrenomedullin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcitonin gene-related peptide receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcitonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calcitonin gene-related peptide type 1 receptor
Names
CGRP type 1 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001102107.1 → NP_001095577.1  calcitonin gene-related peptide type 1 receptor precursor

    See identical proteins and their annotated locations for NP_001095577.1

    Status: PROVISIONAL

    Source sequence(s)
    BC149184
    UniProtKB/Swiss-Prot
    A6QP74
    UniProtKB/TrEMBL
    G3X6P6
    Related
    ENSBTAP00000011169.6, ENSBTAT00000011169.6
    Conserved Domains (2) summary
    pfam02793
    Location:64 → 132
    HRM; Hormone receptor domain
    cd15274
    Location:140 → 403
    7tmB1_calcitonin_R; calcitonin receptor, member of the class B family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    8891723..9020443
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024975202.2 → XP_024830970.1  calcitonin gene-related peptide type 1 receptor isoform X1

    UniProtKB/Swiss-Prot
    A6QP74
    UniProtKB/TrEMBL
    G3X6P6
    Conserved Domains (2) summary
    pfam02793
    Location:64 → 132
    HRM; Hormone receptor domain
    cd15274
    Location:140 → 403
    7tmB1_calcitonin_R; calcitonin receptor, member of the class B family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A6QP74.2 GenPept UniProtKB/Swiss-Prot:A6QP74

Gene LinkOut

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