ADCY9 adenylate cyclase 9 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: ADCY9provided by VGNC
Official Full Name: adenylate cyclase 9provided by VGNC
Primary source: VGNC:VGNC:25650
See related: BGD:BT17617; Ensembl:ENSBTAG00000016629
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 25

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	25	NC_037352.1 (3237659..3349678, complement)

Chromosome 25 - NC_037352.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

this study describes the cryo-electron microscopy structure of the bovine membrane AC9 bound to an activated G protein alphas subunit at 3.4-angstrom resolution.
Title: The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables adenylate cyclase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cyclic nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: adenylate cyclase type 9

NP_001192846.1

EC 4.6.1.1

XP_005224538.1

EC 4.6.1.1

XP_005224539.1

EC 4.6.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001205917.1 → NP_001192846.1 adenylate cyclase type 9

See identical proteins and their annotated locations for NP_001192846.1

Status: PROVISIONAL

Source sequence(s)

NKLS02000025

UniProtKB/TrEMBL

A0A8J8YQJ3, E1BM79, M5FKA2

Conserved Domains (2) summary

smart00044
Location:326 → 544

CYCc; Adenylyl- / guanylyl cyclase, catalytic domain

pfam00211
Location:385 → 573

Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

Range

3237659..3349678 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005224482.5 → XP_005224539.1 adenylate cyclase type 9 isoform X2

See identical proteins and their annotated locations for XP_005224539.1

UniProtKB/TrEMBL

A0A8J8YQJ3, E1BM79, M5FKA2

Conserved Domains (2) summary

smart00044
Location:326 → 544

CYCc; Adenylyl- / guanylyl cyclase, catalytic domain

pfam00211
Location:385 → 573

Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
XM_005224481.5 → XP_005224538.1 adenylate cyclase type 9 isoform X1

Related

ENSBTAP00000022120.6, ENSBTAT00000022120.7

Conserved Domains (3) summary

smart00044
Location:326 → 544

CYCc; Adenylyl- / guanylyl cyclase, catalytic domain

pfam00211
Location:385 → 573

Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain

cl21472
Location:116 → 256

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...