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CAMK2B calcium/calmodulin dependent protein kinase II beta [ Bos taurus (cattle) ]

Gene ID: 525416, updated on 4-Apr-2024

Summary

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Official Symbol
CAMK2Bprovided by VGNC
Official Full Name
calcium/calmodulin dependent protein kinase II betaprovided by VGNC
Primary source
VGNC:VGNC:26722
See related
BGD:BT11211; Ensembl:ENSBTAG00000012653
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See CAMK2B in Genome Data Viewer
Location:
chromosome: 4
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (77025355..77117684)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene NPC1 like intracellular cholesterol transporter 1 Neighboring gene NudC domain containing 3 Neighboring gene uncharacterized LOC104972146 Neighboring gene YKT6 v-SNARE homolog Neighboring gene glucokinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. Aromolaran AS, et al. Am J Physiol Cell Physiol, 2007 Jul. PMID 17344311
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC128545

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calcium/calmodulin-dependent protein kinase type II subunit beta
Names
caM kinase II subunit beta
caM-kinase II beta chain
caMK-II subunit beta
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta
calcium/calmodulin-dependent protein kinase type II beta chain
NP_001030434.1
XP_010802680.1
XP_010802681.1
XP_010802682.1
XP_010802683.1
XP_010802687.1
XP_010802688.1
XP_010802689.1
XP_010802691.1
XP_059741596.1
XP_059741597.1
XP_059741598.1
XP_059741599.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001035357.2 → NP_001030434.1  calcium/calmodulin-dependent protein kinase type II subunit beta

    See identical proteins and their annotated locations for NP_001030434.1

    Status: PROVISIONAL

    Source sequence(s)
    BC105210
    UniProtKB/Swiss-Prot
    Q3MHJ9
    UniProtKB/TrEMBL
    A0A452DIJ8
    Related
    ENSBTAP00000078170.1, ENSBTAT00000111550.1
    Conserved Domains (3) summary
    smart00220
    Location:14 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:410 → 537
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    77025355..77117684
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010804378.4 → XP_010802680.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1

    Related
    ENSBTAP00000099499.1, ENSBTAT00000094423.1
    Conserved Domains (3) summary
    smart00220
    Location:14 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:513 → 640
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  2. XM_059885613.1 → XP_059741596.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X5

  3. XM_010804379.4 → XP_010802681.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X2

    Conserved Domains (3) summary
    smart00220
    Location:14 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:498 → 625
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  4. XM_010804385.4 → XP_010802687.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X7

    UniProtKB/TrEMBL
    A0A452DIJ8
    Conserved Domains (3) summary
    smart00220
    Location:14 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:395 → 522
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  5. XM_010804380.4 → XP_010802682.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X3

    Conserved Domains (3) summary
    smart00220
    Location:14 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:489 → 616
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  6. XM_010804386.4 → XP_010802688.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X8

    UniProtKB/TrEMBL
    A0A452DIJ8
    Conserved Domains (3) summary
    smart00220
    Location:14 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:386 → 513
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  7. XM_059885614.1 → XP_059741597.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X6

    Related
    ENSBTAP00000102818.1, ENSBTAT00000124793.1

  8. XM_010804389.4 → XP_010802691.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X10

    UniProtKB/TrEMBL
    A0A3Q1M9U4, A0A452DIJ8
    Related
    ENSBTAP00000073019.2, ENSBTAT00000084257.2
    Conserved Domains (3) summary
    smart00220
    Location:14 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:371 → 498
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  9. XM_010804381.4 → XP_010802683.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X4

    Conserved Domains (3) summary
    smart00220
    Location:14 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:488 → 615
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  10. XM_010804387.4 → XP_010802689.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X9

    UniProtKB/TrEMBL
    A0A452DIJ8
    Conserved Domains (3) summary
    smart00220
    Location:14 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14086
    Location:12 → 303
    STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
    pfam08332
    Location:385 → 512
    CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

  11. XM_059885616.1 → XP_059741599.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X12

  12. XM_059885615.1 → XP_059741598.1  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X11

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3MHJ9.1 GenPept UniProtKB/Swiss-Prot:Q3MHJ9

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