PTGIR prostaglandin I2 receptor [Bos taurus (cattle)] - Gene

Summary

Official Symbol: PTGIRprovided by VGNC
Official Full Name: prostaglandin I2 receptorprovided by VGNC
Primary source: VGNC:VGNC:49149
See related: BGD:BT22332; Ensembl:ENSBTAG00000014585
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	18	NC_037345.1 (53746036..53756538, complement)

Chromosome 18 - NC_037345.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables prostacyclin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of smooth muscle cell proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cytosolic calcium ion concentration	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prostacyclin receptor

Names: PGI receptor; PGI2 receptor; prostaglandin I2 (prostacyclin) receptor (IP); prostanoid IP receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001015622.2 → NP_001015622.2 prostacyclin receptor

See identical proteins and their annotated locations for NP_001015622.2

Status: PROVISIONAL

Source sequence(s)

NKLS02000018

UniProtKB/Swiss-Prot

P79393

Conserved Domains (2) summary

pfam00001
Location:30 → 292

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:27 → 221

7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

Range

53746036..53756538 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005219278.5 → XP_005219335.1 prostacyclin receptor isoform X1

See identical proteins and their annotated locations for XP_005219335.1

UniProtKB/Swiss-Prot

P79393

UniProtKB/TrEMBL

E1BQ27

Related

ENSBTAP00000019413.4, ENSBTAT00000019413.5

Conserved Domains (2) summary

cd14964
Location:16 → 40

7tm_GPCRs; TM helix 1 [structural motif]

cl28897
Location:14 → 303

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily