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IRS4 insulin receptor substrate 4 [ Bos taurus (cattle) ]

Gene ID: 514607, updated on 5-Mar-2024

Summary

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Official Symbol
IRS4provided by VGNC
Official Full Name
insulin receptor substrate 4provided by VGNC
Primary source
VGNC:VGNC:30285
See related
BGD:BT10405
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (57408199..57424624, complement)

Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene collagen type IV alpha 5 chain Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA U3 Neighboring gene 60S ribosomal protein L31 pseudogene Neighboring gene H2B histone family, member W, testis-specific-like pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables insulin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol 3-kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin receptor substrate 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    57408199..57424624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005227898.3 → XP_005227955.1  insulin receptor substrate 4

    See identical proteins and their annotated locations for XP_005227955.1

    UniProtKB/TrEMBL
    F1MGG8
    Conserved Domains (2) summary
    cd01204
    Location:231 → 334
    PTB_IRS; Insulin receptor substrate phosphotyrosine-binding domain (PTBi)
    cd01257
    Location:77 → 202
    PH_IRS; Insulin receptor substrate (IRS) pleckstrin homology (PH) domain
Nucleotide Protein Strain
Heading Accession and Version

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