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PPP1R12C protein phosphatase 1 regulatory subunit 12C [ Bos taurus (cattle) ]

Gene ID: 512431, updated on 5-Mar-2024

Summary

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Official Symbol
PPP1R12Cprovided by VGNC
Official Full Name
protein phosphatase 1 regulatory subunit 12Cprovided by VGNC
Primary source
VGNC:VGNC:52229
See related
BGD:BT14854; Ensembl:ENSBTAG00000017847
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (62291297..62310501)

Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene troponin I3, cardiac type Neighboring gene troponin T1, slow skeletal type Neighboring gene uncharacterized LOC112442387 Neighboring gene EPS8 like 1 Neighboring gene retinol dehydrogenase 13

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables enzyme inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein phosphatase 1 regulatory subunit 12C
Names
protein phosphatase 1, regulatory (inhibitor) subunit 12C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    62291297..62310501
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024979381.2 → XP_024835149.1  protein phosphatase 1 regulatory subunit 12C isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LWP2
    Conserved Domains (6) summary
    cd00204
    Location:95 → 279
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:100 → 131
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:57 → 131
    Ank_2; Ankyrin repeats (3 copies)
    pfam15898
    Location:683 → 784
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    cl26073
    Location:113 → 225
    Ank_2; Ankyrin repeats (3 copies)
    cl28033
    Location:320 → 700
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  2. XM_024979383.2 → XP_024835151.1  protein phosphatase 1 regulatory subunit 12C isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LWP2
    Related
    ENSBTAP00000065121.2, ENSBTAT00000077989.2
    Conserved Domains (6) summary
    cd00204
    Location:95 → 279
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:100 → 131
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:57 → 131
    Ank_2; Ankyrin repeats (3 copies)
    pfam15898
    Location:683 → 781
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    cl26073
    Location:113 → 225
    Ank_2; Ankyrin repeats (3 copies)
    cl28033
    Location:320 → 700
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  3. XM_024979382.2 → XP_024835150.1  protein phosphatase 1 regulatory subunit 12C isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LWP2
    Conserved Domains (7) summary
    cd00204
    Location:95 → 279
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:100 → 131
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:57 → 131
    Ank_2; Ankyrin repeats (3 copies)
    pfam15898
    Location:682 → 783
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    cl26073
    Location:113 → 225
    Ank_2; Ankyrin repeats (3 copies)
    cl26386
    Location:409 → 631
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    cl28310
    Location:538 → 668
    Rho; Transcription termination factor Rho [Transcription]

  4. XM_024979384.2 → XP_024835152.1  protein phosphatase 1 regulatory subunit 12C isoform X4

    UniProtKB/TrEMBL
    A0A3Q1LWP2
    Conserved Domains (7) summary
    cd00204
    Location:95 → 279
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:100 → 131
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:57 → 131
    Ank_2; Ankyrin repeats (3 copies)
    pfam15898
    Location:682 → 780
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    cl26073
    Location:113 → 225
    Ank_2; Ankyrin repeats (3 copies)
    cl26386
    Location:409 → 631
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    cl28310
    Location:538 → 668
    Rho; Transcription termination factor Rho [Transcription]

  5. XM_024979385.2 → XP_024835153.1  protein phosphatase 1 regulatory subunit 12C isoform X5

    UniProtKB/TrEMBL
    A0A3Q1LWP2
    Conserved Domains (7) summary
    cd00204
    Location:95 → 279
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:100 → 131
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:57 → 131
    Ank_2; Ankyrin repeats (3 copies)
    pfam15898
    Location:665 → 766
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    cl25751
    Location:432 → 595
    DUF4045; Domain of unknown function (DUF4045)
    cl26073
    Location:113 → 225
    Ank_2; Ankyrin repeats (3 copies)
    cl28033
    Location:320 → 648
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
Nucleotide Protein Strain
Heading Accession and Version

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