ADCY2 adenylate cyclase 2 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: ADCY2provided by VGNC
Official Full Name: adenylate cyclase 2provided by VGNC
Primary source: VGNC:VGNC:25643
See related: BGD:BT24683; Ensembl:ENSBTAG00000019210
Gene type: protein coding
RefSeq status: MODEL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	20	NC_037347.1 (65388703..65843081, complement)

Chromosome 20 - NC_037347.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037347.1 Chromosome 20 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These data will serve as a foundation for further insight into the cattle ADCY2 gene.
Title: Molecular cloning, sequence identification, and gene expression analysis of bovine ADCY2 gene.

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

CC541236 (e-PCR)
- UniSTS:476690

ADCY2 (e-PCR)
- UniSTS:479881

ADCY2 (e-PCR)
- UniSTS:277934

AFR2215 (e-PCR), detects polymorphism
- UniSTS:251343

ADCY2 (e-PCR)
- UniSTS:505832

X82432 (e-PCR), detects polymorphism
- UniSTS:251371

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables adenylate cyclase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cAMP biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: adenylate cyclase type 2

XP_024837306.1

EC 4.6.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037347.1 Reference ARS-UCD2.0 Primary Assembly

Range

65388703..65843081 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024981538.2 → XP_024837306.1 adenylate cyclase type 2

UniProtKB/TrEMBL

F1MJV4

Related

ENSBTAP00000095747.1, ENSBTAT00000129107.1

Conserved Domains (3) summary

pfam00211
Location:878 → 1077

Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain

pfam06327
Location:495 → 599

DUF1053; Domain of Unknown Function (DUF1053)

pfam16214
Location:33 → 260

AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region