CHRM5 cholinergic receptor muscarinic 5 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: CHRM5provided by VGNC
Official Full Name: cholinergic receptor muscarinic 5provided by VGNC
Primary source: VGNC:VGNC:10166
Locus tag: CK820_G0049132
See related: Ensembl:ENSPTRG00000006874
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 15

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	16	NC_072414.2 (25943647..25993118)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	15	NC_072413.1 (25940265..25989956)

Chromosome 16 - NC_072414.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled acetylcholine receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables G protein-coupled serotonin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IEA Inferred from Electronic Annotation more info	PubMed
involved_in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chemical synaptic transmission	IEA Inferred from Electronic Annotation more info	PubMed
involved_in gastric acid secretion	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in dendrite	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in synapse	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: muscarinic acetylcholine receptor M5

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001012442.2 → NP_001012444.2 muscarinic acetylcholine receptor M5

Status: VALIDATED

Source sequence(s)

JAQQLN020000016

UniProtKB/TrEMBL

A0A2J8JB58, A0A6D2XJT1, H2Q935

Conserved Domains (3) summary

cd14964
Location:438 → 463

7tm_GPCRs; TM helix 6 [structural motif]

cd15300
Location:31 → 225

7tmA_mAChR_M5; muscarinic receptor subtype M5, member of the class A family of seven-transmembrane G protein-coupled receptors

cl28897
Location:435 → 514

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily