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Gpr62 G protein-coupled receptor 62 [ Rattus norvegicus (Norway rat) ]

Gene ID: 501049, updated on 13-Apr-2024

Summary

Official Symbol
Gpr62provided by RGD
Official Full Name
G protein-coupled receptor 62provided by RGD
Primary source
RGD:1560166
See related
Ensembl:ENSRNOG00000022567 AllianceGenome:RGD:1560166
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1560166
Summary
Predicted to enable G protein-coupled receptor activity; arrestin family protein binding activity; and identical protein binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway; inositol phosphate-mediated signaling; and positive regulation of cAMP-mediated signaling. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in endosome and plasma membrane. Orthologous to human GPR62 (G protein-coupled receptor 62). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
8q32
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (115981936..115984022, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (107103225..107105311, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (115165655..115170396, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 14A Neighboring gene uncharacterized LOC134480228 Neighboring gene abhydrolase domain containing 14b Neighboring gene poly(rC) binding protein 4 Neighboring gene poly (ADP-ribose) polymerase family, member 3 Neighboring gene ribosomal RNA processing 9, U3 small nucleolar RNA binding protein Neighboring gene IQ motif containing F1

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables arrestin family protein binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
part_of receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of receptor complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
G-protein coupled receptor 62
Names
probable G-protein coupled receptor 62

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398913.1NP_001385842.1  G-protein coupled receptor 62

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    D4A2B1
    Related
    ENSRNOP00000038558.2, ENSRNOT00000033018.3
    Conserved Domains (2) summary
    cd14964
    Location:1642
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:16297
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    115981936..115984022 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)