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Opn3 opsin 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 498289, updated on 4-Jan-2025

Summary

Official Symbol
Opn3provided by RGD
Official Full Name
opsin 3provided by RGD
Primary source
RGD:1594385
See related
EnsemblRapid:ENSRNOG00000003778 AllianceGenome:RGD:1594385
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable 11-cis retinal binding activity; G protein-coupled photoreceptor activity; and all-trans retinal binding activity. Predicted to be involved in several processes, including cellular response to UV-A; positive regulation of D-glucose import; and regulation of melanin biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in photoreceptor outer segment and plasma membrane. Orthologous to human OPN3 (opsin 3). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Kidney (RPKM 36.9), Brain (RPKM 32.7) and 9 other tissues See more
Orthologs
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Genomic context

See Opn3 in Genome Data Viewer
Location:
13q24
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (90121560..90152076, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (87589333..87619847, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (93716481..93746994, complement)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene fumarate hydratase Neighboring gene uncharacterized LOC134481597 Neighboring gene kynurenine 3-monooxygenase Neighboring gene small ribosomal subunit protein eS1-like Neighboring gene CHM like Rab escort protein Neighboring gene WD repeat domain 64 Neighboring gene uncharacterized LOC103692323 Neighboring gene uncharacterized LOC103692322 Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables 11-cis retinal binding  
enables G protein-coupled photoreceptor activity  
enables all-trans retinal binding  
Component Evidence Code Pubs
located_in cytoplasm  
is_active_in photoreceptor outer segment  
is_active_in plasma membrane  
located_in plasma membrane  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191933.1NP_001178862.1  opsin-3

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000013
    UniProtKB/TrEMBL
    D3ZFS1
    Related
    ENSRNOP00000005072.3, ENSRNOT00000005072.7
    Conserved Domains (2) summary
    cd14964
    Location:74101
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:64317
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    90121560..90152076 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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