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fgf14 fibroblast growth factor 14 [ Danio rerio (zebrafish) ]

Gene ID: 497642, updated on 27-Mar-2024

Summary

Official Symbol
fgf14provided by ZNC
Official Full Name
fibroblast growth factor 14provided by ZNC
Primary source
ZFIN:ZDB-GENE-060506-1
See related
Ensembl:ENSDARG00000040982 AllianceGenome:ZFIN:ZDB-GENE-060506-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable sodium channel regulator activity. Predicted to be involved in regulation of voltage-gated sodium channel activity. Predicted to act upstream of or within nervous system development. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 27. Orthologous to human FGF14 (fibroblast growth factor 14). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 9
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (31835221..32051533, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (32024994..32240695, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene sodium leak channel, non-selective Neighboring gene uncharacterized LOC110437732 Neighboring gene integrin, beta-like 1 Neighboring gene uncharacterized LOC103911668 Neighboring gene CFAP97 domain containing 2 Neighboring gene phosphoinositide kinase, FYVE finger containing

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 
enables sodium channel regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in regulation of voltage-gated sodium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
fibroblast growth factor 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012382.1NP_001012382.1  fibroblast growth factor 14

    See identical proteins and their annotated locations for NP_001012382.1

    Status: PROVISIONAL

    Source sequence(s)
    AB195620
    UniProtKB/TrEMBL
    B3DHQ7, Q5TKR1
    Related
    ENSDARP00000060050.4, ENSDART00000060051.5
    Conserved Domains (1) summary
    pfam00167
    Location:72197
    FGF; Fibroblast growth factor

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    31835221..32051533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009304735.3XP_009303010.1  fibroblast growth factor 14 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AW31
    Conserved Domains (1) summary
    pfam00167
    Location:38163
    FGF; Fibroblast growth factor
  2. XM_021478647.1XP_021334322.1  fibroblast growth factor 14 isoform X3

    UniProtKB/TrEMBL
    A0A8M2BF45
    Conserved Domains (1) summary
    pfam00167
    Location:1113
    FGF; Fibroblast growth factor
  3. XM_021478646.1XP_021334321.1  fibroblast growth factor 14 isoform X2

    UniProtKB/TrEMBL
    A0A8M9QFC2
    Conserved Domains (1) summary
    pfam00167
    Location:31156
    FGF; Fibroblast growth factor
  4. XM_005167695.4XP_005167752.1  fibroblast growth factor 14 isoform X3

    See identical proteins and their annotated locations for XP_005167752.1

    UniProtKB/TrEMBL
    A0A8M2BF45
    Conserved Domains (1) summary
    pfam00167
    Location:1113
    FGF; Fibroblast growth factor