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PRKCD protein kinase C delta [ Canis lupus familiaris (dog) ]

Gene ID: 494005, updated on 5-Mar-2024

Summary

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Official Symbol
PRKCDprovided by VGNC
Official Full Name
protein kinase C deltaprovided by VGNC
Primary source
VGNC:VGNC:44979
See related
Ensembl:ENSCAFG00845028762
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See PRKCD in Genome Data Viewer
Location:
chromosome: 20
Exon count:
21
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (37001697..37030998, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (36660459..36673894, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (37015742..37029186, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (36438983..36452419, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (36800686..36814133, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene transketolase Neighboring gene uncharacterized LOC111091444 Neighboring gene uncharacterized LOC111091315 Neighboring gene RFT1 homolog Neighboring gene cytochrome c oxidase assembly protein COX19-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables diacylglycerol-dependent serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein kinase C delta type
Names
nPKC-delta
tyrosine-protein kinase PRKCD
NP_001008716.1
XP_038282422.1
XP_038282423.1
XP_038282424.1
XP_038282425.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008716.1 → NP_001008716.1  protein kinase C delta type

    See identical proteins and their annotated locations for NP_001008716.1

    Status: PROVISIONAL

    Source sequence(s)
    AY825360
    UniProtKB/Swiss-Prot
    Q5PU49
    UniProtKB/TrEMBL
    A0A8C0PZJ7, A0A8C0T441, A0A8I3Q187, A0A8P0NWP8
    Conserved Domains (3) summary
    smart00220
    Location:347 → 601
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    pfam00130
    Location:231 → 283
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    cl21453
    Location:351 → 666
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    37001697..37030998 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038426495.1 → XP_038282423.1  protein kinase C delta type isoform X2

    UniProtKB/TrEMBL
    A0A8C0PZJ7, A0A8C0T441, A0A8I3Q187, A0A8P0NWP8
    Conserved Domains (3) summary
    cd20834
    Location:152 → 212
    C1_nPKC_theta-like_rpt1; first protein kinase C conserved region 1 (C1 domain) found in novel protein kinase C (nPKC) theta, delta, and similar proteins
    cd20837
    Location:231 → 280
    C1_nPKC_theta-like_rpt2; second protein kinase C conserved region 1 (C1 domain) found in novel protein kinase C (nPKC) theta, delta, and similar proteins
    cl21453
    Location:349 → 664
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038426494.1 → XP_038282422.1  protein kinase C delta type isoform X1

    UniProtKB/TrEMBL
    A0A8C0PZJ7, A0A8C0QVC9, A0A8C0RU27, A0A8C0T441, A0A8I3PZJ7, A0A8I3Q187, A0A8P0NWP8
    Related
    ENSCAFP00845039871.1, ENSCAFT00845050861.1
    Conserved Domains (3) summary
    cd20834
    Location:152 → 212
    C1_nPKC_theta-like_rpt1; first protein kinase C conserved region 1 (C1 domain) found in novel protein kinase C (nPKC) theta, delta, and similar proteins
    cd20837
    Location:231 → 280
    C1_nPKC_theta-like_rpt2; second protein kinase C conserved region 1 (C1 domain) found in novel protein kinase C (nPKC) theta, delta, and similar proteins
    cl21453
    Location:351 → 666
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038426497.1 → XP_038282425.1  protein kinase C delta type isoform X4

    UniProtKB/TrEMBL
    A0A8C0PZJ7, A0A8C0T441, A0A8I3Q187, A0A8P0NWP8
    Conserved Domains (3) summary
    cd20834
    Location:115 → 175
    C1_nPKC_theta-like_rpt1; first protein kinase C conserved region 1 (C1 domain) found in novel protein kinase C (nPKC) theta, delta, and similar proteins
    cd20837
    Location:194 → 243
    C1_nPKC_theta-like_rpt2; second protein kinase C conserved region 1 (C1 domain) found in novel protein kinase C (nPKC) theta, delta, and similar proteins
    cl21453
    Location:314 → 629
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038426496.1 → XP_038282424.1  protein kinase C delta type isoform X3

    UniProtKB/TrEMBL
    A0A8P0NU01, A0A8P0PGP6
    Conserved Domains (3) summary
    cd20834
    Location:152 → 212
    C1_nPKC_theta-like_rpt1; first protein kinase C conserved region 1 (C1 domain) found in novel protein kinase C (nPKC) theta, delta, and similar proteins
    cd20837
    Location:231 → 280
    C1_nPKC_theta-like_rpt2; second protein kinase C conserved region 1 (C1 domain) found in novel protein kinase C (nPKC) theta, delta, and similar proteins
    cl21453
    Location:351 → 622
    PKc_like; Protein Kinases, catalytic domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    36438983..36452419 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    36800686..36814133 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    37015742..37029186 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    36660459..36673894 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5PU49.1 GenPept UniProtKB/Swiss-Prot:Q5PU49

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