RHO rhodopsin [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: RHOprovided by VGNC
Official Full Name: rhodopsinprovided by VGNC
Primary source: VGNC:VGNC:45554
See related: Ensembl:ENSCAFG00845027581
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: RHO1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	20	NC_051824.1 (5661948..5667219, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	20	NC_006602.4 (5669643..5674903, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	20	NC_049241.1 (5706443..5711705, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	20	NC_049280.1 (5377793..5383047, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	20	NC_049761.1 (5730818..5736090, complement)

Chromosome 20 - NC_051824.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

mechanisms of retinal neuronal injury, repair, compensation, and degeneration in the rhodopsin mutant dog
Title: In vivo dynamics of retinal injury and repair in the rhodopsin mutant dog model of human retinitis pigmentosa.

Submit: New GeneRIF Correction

General gene information

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Markers

RHO (e-PCR), detects polymorphism
- UniSTS:264837

RHO (e-PCR), detects polymorphism
- UniSTS:279020

RHO-5UUTR (e-PCR)
- UniSTS:15355

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phototransduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in visual perception	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in photoreceptor outer segment	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: rhodopsin

Names: opsin; rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant); rod opsin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008276.1 → NP_001008277.1 rhodopsin

See identical proteins and their annotated locations for NP_001008277.1

Status: PROVISIONAL

Source sequence(s)

Y09004

UniProtKB/TrEMBL

A0A8C0P150, A0A8I3QE57

Related

ENSCAFP00845038150.1, ENSCAFT00845048633.1

Conserved Domains (2) summary

pfam10413
Location:3 → 37

Rhodopsin_N; Amino terminal of the G-protein receptor rhodopsin

cd15080
Location:38 → 327

7tmA_MWS_opsin; medium wave-sensitive opsins, member of the class A family of seven-transmembrane G protein-coupled receptors