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fgf7 fibroblast growth factor 7 [ Danio rerio (zebrafish) ]

Gene ID: 493181, updated on 11-Apr-2024

Summary

Official Symbol
fgf7provided by ZNC
Official Full Name
fibroblast growth factor 7provided by ZNC
Primary source
ZFIN:ZDB-GENE-080122-1
See related
Ensembl:ENSDARG00000059387 AllianceGenome:ZFIN:ZDB-GENE-080122-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable growth factor activity and type 2 fibroblast growth factor receptor binding activity. Predicted to be involved in several processes, including animal organ development; fibroblast growth factor receptor signaling pathway; and positive regulation of macromolecule metabolic process. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Orthologous to human FGF7 (fibroblast growth factor 7). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 18
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (5423251..5442200)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (5406488..5424077, complement)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene fibrillin 1 Neighboring gene SECIS binding protein 2-like Neighboring gene uncharacterized LOC103909114 Neighboring gene NAD(P) transhydrogenase, mitochondrial Neighboring gene DTW domain containing 1 Neighboring gene uncharacterized LOC103909115

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables growth factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 
enables type 2 fibroblast growth factor receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in fibroblast growth factor receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in lung development IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of epithelial cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of peptidyl-tyrosine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007761.1NP_001007762.1  fibroblast growth factor 7 precursor

    See identical proteins and their annotated locations for NP_001007762.1

    Status: PROVISIONAL

    Source sequence(s)
    AB194727
    UniProtKB/TrEMBL
    Q5TLD5
    Related
    ENSDARP00000122453.1, ENSDART00000139752.2
    Conserved Domains (1) summary
    pfam00167
    Location:43168
    FGF; Fibroblast growth factor

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    5423251..5442200
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009293389.3XP_009291664.1  fibroblast growth factor 7 isoform X1

    See identical proteins and their annotated locations for XP_009291664.1

    UniProtKB/TrEMBL
    B3DHR9, B3DHV2, F6NW91
    Conserved Domains (1) summary
    pfam00167
    Location:43168
    FGF; Fibroblast growth factor