snrpa1 small nuclear ribonucleoprotein polypeptide A' [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: snrpa1provided by ZNC
Official Full Name: small nuclear ribonucleoprotein polypeptide A'provided by ZNC
Primary source: ZFIN:ZDB-GENE-041114-82
See related: Ensembl:ENSDARG00000024651 AllianceGenome:ZFIN:ZDB-GENE-041114-82
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7142962; zgc:101832
Summary: Predicted to enable U2 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U2 snRNP. Is expressed in female organism. Human ortholog(s) of this gene implicated in connective tissue disease. Orthologous to human SNRPA1 (small nuclear ribonucleoprotein polypeptide A'). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (9290934..9305587)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (9045444..9060099)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables U2 snRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of U2 snRNP	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: U2 small nuclear ribonucleoprotein A'

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001007383.2 → NP_001007384.2 U2 small nuclear ribonucleoprotein A'

Status: VALIDATED

Source sequence(s)

CU856378, EH529176, EH548169

UniProtKB/TrEMBL

A0A8M1N398, F1R300

Related

ENSDARP00000107467.2, ENSDART00000128530.4

Conserved Domains (4) summary

smart00446
Location:128 → 146

LRRcap; occurring C-terminal to leucine-rich repeats

pfam14580
Location:1 → 175

LRR_9; Leucine-rich repeat

sd00031
Location:46 → 65

LRR_1; leucine-rich repeat [structural motif]

pfam12799
Location:64 → 108

LRR_4; Leucine Rich repeats (2 copies)