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CAPN6 calpain 6 [ Canis lupus familiaris (dog) ]

Gene ID: 492068, updated on 5-Mar-2024

Summary

Official Symbol
CAPN6provided by VGNC
Official Full Name
calpain 6provided by VGNC
Primary source
VGNC:VGNC:38706
See related
Ensembl:ENSCAFG00845022341
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See CAPN6 in Genome Data Viewer
Location:
chromosome: X
Exon count:
13
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (86013239..86039076, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (70452893..70478661, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (85002271..85028105, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (83496162..83521922, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (85173775..85199625, complement)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119868500 Neighboring gene p21 (RAC1) activated kinase 3 Neighboring gene U6 spliceosomal RNA Neighboring gene doublecortin Neighboring gene U4 spliceosomal RNA Neighboring gene transcriptional adapter 3-like

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    86013239..86039076 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038450652.1XP_038306580.1  calpain-6

    UniProtKB/TrEMBL
    A0A8C0JW52, A0A8C0QVM2, A0A8C0SR05, A0A8I3PJW4
    Related
    ENSCAFP00845030899.1, ENSCAFT00845039430.1
    Conserved Domains (3) summary
    smart00230
    Location:13351
    CysPc; Calpain-like thiol protease family
    cd04046
    Location:514639
    C2_Calpain; C2 domain present in Calpain proteins
    cd00214
    Location:349497
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    83496162..83521922 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038524116.1XP_038380044.1  calpain-6

    Conserved Domains (3) summary
    smart00230
    Location:13351
    CysPc; Calpain-like thiol protease family
    cd04046
    Location:514639
    C2_Calpain; C2 domain present in Calpain proteins
    cd00214
    Location:349497
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    85173775..85199625 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038652608.1XP_038508536.1  calpain-6

    Conserved Domains (3) summary
    smart00230
    Location:13351
    CysPc; Calpain-like thiol protease family
    cd04046
    Location:514639
    C2_Calpain; C2 domain present in Calpain proteins
    cd00214
    Location:349497
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    85002271..85028105 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038588092.1XP_038444020.1  calpain-6

    UniProtKB/TrEMBL
    A0A8C0JW52, A0A8C0QVM2, A0A8C0SR05, A0A8I3PJW4
    Conserved Domains (3) summary
    smart00230
    Location:13351
    CysPc; Calpain-like thiol protease family
    cd04046
    Location:514639
    C2_Calpain; C2 domain present in Calpain proteins
    cd00214
    Location:349497
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    70452893..70478661 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_549188.7XP_549188.2  calpain-6

    UniProtKB/TrEMBL
    A0A8C0JW52, A0A8C0QVM2, A0A8C0SR05, A0A8I3PJW4
    Conserved Domains (3) summary
    smart00230
    Location:13351
    CysPc; Calpain-like thiol protease family
    cd04046
    Location:514639
    C2_Calpain; C2 domain present in Calpain proteins
    cd00214
    Location:349497
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...