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GRB7 growth factor receptor bound protein 7 [ Canis lupus familiaris (dog) ]

Gene ID: 491021, updated on 5-Mar-2024

Summary

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Official Symbol
GRB7provided by VGNC
Official Full Name
growth factor receptor bound protein 7provided by VGNC
Primary source
VGNC:VGNC:41473
See related
Ensembl:ENSCAFG00845011327
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
17
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (23536867..23545435, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (22215830..22224392, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (22695812..22704377, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (22309656..22318216, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (22570695..22579250, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene zona pellucida binding protein 2 Neighboring gene IKAROS family zinc finger 3 Neighboring gene uncharacterized LOC111097358 Neighboring gene migration and invasion enhancer 1 Neighboring gene erb-b2 receptor tyrosine kinase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
growth factor receptor-bound protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    23536867..23545435 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038676596.1 → XP_038532524.1  growth factor receptor-bound protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  2. XM_038676599.1 → XP_038532527.1  growth factor receptor-bound protein 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Related
    ENSCAFP00845015951.1, ENSCAFT00845020349.1
    Conserved Domains (3) summary
    cd10413
    Location:384 → 491
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7

  3. XM_038676595.1 → XP_038532523.1  growth factor receptor-bound protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Related
    ENSCAFP00845015739.1, ENSCAFT00845020085.1
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  4. XM_038676598.1 → XP_038532526.1  growth factor receptor-bound protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  5. XM_038676597.1 → XP_038532525.1  growth factor receptor-bound protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    22309656..22318216 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038485650.1 → XP_038341578.1  growth factor receptor-bound protein 7 isoform X1

    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  2. XM_038485653.1 → XP_038341581.1  growth factor receptor-bound protein 7 isoform X2

    Conserved Domains (3) summary
    cd10413
    Location:384 → 491
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7

  3. XM_038485649.1 → XP_038341577.1  growth factor receptor-bound protein 7 isoform X1

    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  4. XM_038485652.1 → XP_038341580.1  growth factor receptor-bound protein 7 isoform X1

    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  5. XM_038485651.1 → XP_038341579.1  growth factor receptor-bound protein 7 isoform X1

    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    22570695..22579250 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038611400.1 → XP_038467328.1  growth factor receptor-bound protein 7 isoform X1

    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  2. XM_038611403.1 → XP_038467331.1  growth factor receptor-bound protein 7 isoform X2

    Conserved Domains (3) summary
    cd10413
    Location:384 → 491
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7

  3. XM_038611399.1 → XP_038467327.1  growth factor receptor-bound protein 7 isoform X1

    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  4. XM_038611402.1 → XP_038467330.1  growth factor receptor-bound protein 7 isoform X1

    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  5. XM_038611401.1 → XP_038467329.1  growth factor receptor-bound protein 7 isoform X1

    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    22695812..22704377 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038547418.1 → XP_038403346.1  growth factor receptor-bound protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  2. XM_038547421.1 → XP_038403349.1  growth factor receptor-bound protein 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (3) summary
    cd10413
    Location:384 → 491
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7

  3. XM_038547416.1 → XP_038403344.1  growth factor receptor-bound protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  4. XM_038547420.1 → XP_038403348.1  growth factor receptor-bound protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  5. XM_038547419.1 → XP_038403347.1  growth factor receptor-bound protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    22215830..22224392 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_548141.6 → XP_548141.2  growth factor receptor-bound protein 7 isoform X1

    See identical proteins and their annotated locations for XP_548141.2

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  2. XM_005624551.3 → XP_005624608.1  growth factor receptor-bound protein 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (3) summary
    cd10413
    Location:384 → 491
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7

  3. XM_005624550.3 → XP_005624607.1  growth factor receptor-bound protein 7 isoform X1

    See identical proteins and their annotated locations for XP_005624607.1

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  4. XM_022423016.2 → XP_022278724.1  growth factor receptor-bound protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)

  5. XM_022423015.2 → XP_022278723.1  growth factor receptor-bound protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KYQ9
    Conserved Domains (4) summary
    cd10413
    Location:423 → 530
    SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
    cd01259
    Location:225 → 347
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16140
    Location:101 → 187
    RA_GRB7; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 7
    pfam08947
    Location:366 → 408
    BPS; BPS (Between PH and SH2)
Nucleotide Protein
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