U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

STAT5A signal transducer and activator of transcription 5A [ Canis lupus familiaris (dog) ]

Gene ID: 490968, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
STAT5Aprovided by VGNC
Official Full Name
signal transducer and activator of transcription 5Aprovided by VGNC
Primary source
VGNC:VGNC:46891
See related
Ensembl:ENSCAFG00845009709
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 9
Exon count:
21
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (21335685..21357957, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (20077547..20099955, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (20490411..20512845, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (20120814..20142574, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (20387762..20409305, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene caveolae associated protein 1 Neighboring gene signal transducer and activator of transcription 3 Neighboring gene uncharacterized LOC119873266 Neighboring gene proline-rich protein HaeIII subfamily 1-like Neighboring gene signal transducer and activator of transcription 5B

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
LOW QUALITY PROTEIN: signal transducer and activator of transcription 5A; signal transducer and activator of transcription 5A

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    21335685..21357957 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038676449.1 → XP_038532377.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    A0A8C0LRK1, A0A8C0R0C0, A0A8C0S0L9, A0A8I3RVE7, A0A8P0SJX7
    Conserved Domains (4) summary
    cd10421
    Location:573 → 712
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain

  2. XM_038676448.1 → XP_038532376.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    A0A8C0LRK1, A0A8C0R0C0, A0A8C0S0L9, A0A8I3RVE7, A0A8P0SJX7
    Related
    ENSCAFP00845013361.1, ENSCAFT00845017149.1
    Conserved Domains (4) summary
    cd10421
    Location:573 → 712
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain

  3. XM_038676450.1 → XP_038532378.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    A0A8C0LS22, A0A8I3N824
    Conserved Domains (3) summary
    cd10421
    Location:437 → 576
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:3 → 194
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:196 → 353
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    20120814..20142574 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038485526.1 → XP_038341454.1  LOW QUALITY PROTEIN: signal transducer and activator of transcription 5A isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    20387762..20409305 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038610048.1 → XP_038465976.1  signal transducer and activator of transcription 5A isoform X3

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    20490411..20512845 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038547291.1 → XP_038403219.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    A0A8C0LRK1, A0A8C0R0C0, A0A8C0S0L9, A0A8I3RVE7, A0A8P0SJX7
    Conserved Domains (4) summary
    cd10421
    Location:573 → 712
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain

  2. XM_038547290.1 → XP_038403218.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    A0A8C0LRK1, A0A8C0R0C0, A0A8C0S0L9, A0A8I3RVE7, A0A8P0SJX7
    Conserved Domains (4) summary
    cd10421
    Location:573 → 712
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain

  3. XM_038547292.1 → XP_038403220.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    A0A8C0LS22, A0A8I3N824
    Conserved Domains (3) summary
    cd10421
    Location:437 → 576
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:3 → 194
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:196 → 353
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    20077547..20099955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022422985.2 → XP_022278693.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    A0A8C0LRK1, A0A8C0R0C0, A0A8C0S0L9, A0A8I3RVE7, A0A8P0SJX7
    Conserved Domains (4) summary
    cd10421
    Location:573 → 712
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain

  2. XM_038602725.1 → XP_038458653.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    A0A8C0LRK1, A0A8C0R0C0, A0A8C0S0L9, A0A8I3RVE7, A0A8P0SJX7
    Conserved Domains (4) summary
    cd10421
    Location:573 → 712
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain

  3. XM_005624460.4 → XP_005624517.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    A0A8C0LS22, A0A8I3N824
    Conserved Domains (3) summary
    cd10421
    Location:437 → 576
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:3 → 194
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:196 → 353
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous