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FZD2 frizzled class receptor 2 [ Canis lupus familiaris (dog) ]

Gene ID: 490937, updated on 5-Mar-2024

Summary

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Official Symbol
FZD2provided by VGNC
Official Full Name
frizzled class receptor 2provided by VGNC
Primary source
VGNC:VGNC:41030
See related
Ensembl:ENSCAFG00845007799
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
1
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (19578886..19581949, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (18275000..18278038, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (18760592..18763652, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (18433221..18436253, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (18616401..18619457, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119880055 Neighboring gene small nucleolar RNA SNORA33 Neighboring gene uncharacterized LOC111097345 Neighboring gene G-patch domain containing 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Caveolin-1 down-regulation is required for Wnt5a-Frizzled 2 signalling in Ha-Ras(V12) -induced cell transformation. Lin HK, et al. J Cell Mol Med, 2018 May. PMID 29502342, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
frizzled-2
Names
frizzled 2, seven transmembrane spanning receptor
frizzled family receptor 2
frizzled homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    19578886..19581949 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038675184.1 → XP_038531112.1  frizzled-2

    UniProtKB/TrEMBL
    A0A8C0K7J1, A0A8I3N4R2, A0A8P0SIN7
    Related
    ENSCAFP00845010636.1, ENSCAFT00845013702.1
    Conserved Domains (2) summary
    cd07464
    Location:35 → 161
    CRD_FZ2; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 2 (Fz2) receptor
    cd15245
    Location:234 → 563
    7tmF_FZD2; class F frizzled subfamily 2, member of 7-transmembrane G protein-coupled receptors

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    18433221..18436253 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038487589.1 → XP_038343517.1  frizzled-2

    Conserved Domains (2) summary
    cd07464
    Location:35 → 161
    CRD_FZ2; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 2 (Fz2) receptor
    cd15245
    Location:234 → 563
    7tmF_FZD2; class F frizzled subfamily 2, member of 7-transmembrane G protein-coupled receptors

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    18616401..18619457 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038610119.1 → XP_038466047.1  frizzled-2

    Conserved Domains (2) summary
    cd07464
    Location:35 → 161
    CRD_FZ2; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 2 (Fz2) receptor
    cd15245
    Location:234 → 563
    7tmF_FZD2; class F frizzled subfamily 2, member of 7-transmembrane G protein-coupled receptors

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    18760592..18763652 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038546095.1 → XP_038402023.1  frizzled-2

    UniProtKB/TrEMBL
    A0A8C0K7J1, A0A8I3N4R2, A0A8P0SIN7
    Conserved Domains (2) summary
    cd07464
    Location:35 → 161
    CRD_FZ2; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 2 (Fz2) receptor
    cd15245
    Location:234 → 563
    7tmF_FZD2; class F frizzled subfamily 2, member of 7-transmembrane G protein-coupled receptors

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    18275000..18278038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_548060.6 → XP_548060.2  frizzled-2

    See identical proteins and their annotated locations for XP_548060.2

    UniProtKB/TrEMBL
    A0A8C0K7J1, A0A8I3N4R2, A0A8P0SIN7
    Conserved Domains (2) summary
    cd07464
    Location:35 → 161
    CRD_FZ2; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 2 (Fz2) receptor
    cd15245
    Location:234 → 563
    7tmF_FZD2; class F frizzled subfamily 2, member of 7-transmembrane G protein-coupled receptors
Nucleotide Protein
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