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RPS6KA5 ribosomal protein S6 kinase A5 [ Canis lupus familiaris (dog) ]

Gene ID: 490831, updated on 5-Mar-2024

Summary

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Official Symbol
RPS6KA5provided by VGNC
Official Full Name
ribosomal protein S6 kinase A5provided by VGNC
Primary source
VGNC:VGNC:45742
See related
Ensembl:ENSCAFG00845013465
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
19
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (62076158..62246525, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (61381750..61551905, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (62135192..62305546, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (61756580..61926684, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (61805735..61976310, complement)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 7B Neighboring gene uncharacterized LOC119872920 Neighboring gene uncharacterized LOC102157222 Neighboring gene uncharacterized LOC111097242 Neighboring gene pyruvate dehydrogenase E1 component subunit beta, mitochondrial-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ribosomal protein S6 kinase alpha-5; LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-5
XP_022278039.1
XP_022278040.1
XP_038339983.1
XP_038401484.1
XP_038401485.1
XP_038401486.1
XP_038401487.1
XP_038449776.1
XP_038449781.1
XP_038465579.1
XP_038465580.1
XP_038465581.1
XP_038465582.1
XP_038530388.1
XP_038530389.1
XP_038530390.1
XP_038530391.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    62076158..62246525 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038674461.1 → XP_038530389.1  ribosomal protein S6 kinase alpha-5 isoform X2

    UniProtKB/TrEMBL
    A0A8C0M2X3
    Related
    ENSCAFP00845018966.1, ENSCAFT00845024148.1
    Conserved Domains (2) summary
    cd14179
    Location:397 → 706
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:38 → 359
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038674460.1 → XP_038530388.1  ribosomal protein S6 kinase alpha-5 isoform X1

    UniProtKB/TrEMBL
    A0A8C0M2X3
    Related
    ENSCAFP00845018911.1, ENSCAFT00845024077.1
    Conserved Domains (2) summary
    cd14179
    Location:421 → 730
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:51 → 383
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038674462.1 → XP_038530390.1  ribosomal protein S6 kinase alpha-5 isoform X3

    Conserved Domains (2) summary
    cd14179
    Location:199 → 508
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 161
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038674463.1 → XP_038530391.1  ribosomal protein S6 kinase alpha-5 isoform X4

    Conserved Domains (2) summary
    cd14179
    Location:137 → 446
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 99
    PKc_like; Protein Kinases, catalytic domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    61756580..61926684 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038484055.1 → XP_038339983.1  LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-5 isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    61805735..61976310 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038609652.1 → XP_038465580.1  ribosomal protein S6 kinase alpha-5 isoform X2

  2. XM_038609651.1 → XP_038465579.1  ribosomal protein S6 kinase alpha-5 isoform X1

  3. XM_038609653.1 → XP_038465581.1  ribosomal protein S6 kinase alpha-5 isoform X3

    Conserved Domains (2) summary
    cd14179
    Location:199 → 508
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 161
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038609654.1 → XP_038465582.1  ribosomal protein S6 kinase alpha-5 isoform X4

    Conserved Domains (2) summary
    cd14179
    Location:137 → 446
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 99
    PKc_like; Protein Kinases, catalytic domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    62135192..62305546 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038545557.1 → XP_038401485.1  ribosomal protein S6 kinase alpha-5 isoform X2

    UniProtKB/TrEMBL
    A0A8C0M2X3

  2. XM_038545556.1 → XP_038401484.1  ribosomal protein S6 kinase alpha-5 isoform X1

    UniProtKB/TrEMBL
    A0A8C0M2X3

  3. XM_038545558.1 → XP_038401486.1  ribosomal protein S6 kinase alpha-5 isoform X3

    Conserved Domains (2) summary
    cd14179
    Location:199 → 508
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 161
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038545559.1 → XP_038401487.1  ribosomal protein S6 kinase alpha-5 isoform X4

    Conserved Domains (2) summary
    cd14179
    Location:137 → 446
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 99
    PKc_like; Protein Kinases, catalytic domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    61381750..61551905 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038593853.1 → XP_038449781.1  ribosomal protein S6 kinase alpha-5 isoform X2

    UniProtKB/TrEMBL
    A0A8C0M2X3
    Conserved Domains (2) summary
    cd14179
    Location:397 → 706
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:38 → 359
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038593848.1 → XP_038449776.1  ribosomal protein S6 kinase alpha-5 isoform X1

    UniProtKB/TrEMBL
    A0A8C0M2X3
    Conserved Domains (2) summary
    cd14179
    Location:421 → 730
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:51 → 383
    PKc_like; Protein Kinases, catalytic domain

  3. XM_022422331.2 → XP_022278039.1  ribosomal protein S6 kinase alpha-5 isoform X3

    Conserved Domains (2) summary
    cd14179
    Location:199 → 508
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 161
    PKc_like; Protein Kinases, catalytic domain

  4. XM_022422332.2 → XP_022278040.1  ribosomal protein S6 kinase alpha-5 isoform X4

    Conserved Domains (2) summary
    cd14179
    Location:137 → 446
    STKc_MSK1_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 1
    cl21453
    Location:1 → 99
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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