RALBP1 ralA binding protein 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: RALBP1provided by VGNC
Official Full Name: ralA binding protein 1provided by VGNC
Primary source: VGNC:VGNC:45332
See related: Ensembl:ENSCAFG00845004603
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	7	NC_051811.1 (75516008..75571183)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	7	NC_006589.4 (74854142..74908610)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	7	NC_049228.1 (75541877..75596810)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	7	NC_049267.1 (75213986..75269336)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	7	NC_049748.1 (75231509..75286643)

Chromosome 7 - NC_051811.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MDR1 Inhibition Reverses Doxorubicin-Resistance in Six Doxorubicin-Resistant Canine Prostate and Bladder Cancer Cell Lines.
Title: MDR1 Inhibition Reverses Doxorubicin-Resistance in Six Doxorubicin-Resistant Canine Prostate and Bladder Cancer Cell Lines.

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info	PubMed
enables small GTPase binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in endocytosis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in small GTPase-mediated signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ralA-binding protein 1

XP_038338331.1

EC 7.6.2.2

EC 7.6.2.3

XP_038338332.1

EC 7.6.2.2

EC 7.6.2.3

XP_038338333.1

EC 7.6.2.2

EC 7.6.2.3

XP_038338334.1

EC 7.6.2.2

EC 7.6.2.3

XP_038399783.1

EC 7.6.2.2

EC 7.6.2.3

XP_038399784.1

EC 7.6.2.2

EC 7.6.2.3

XP_038399785.1

EC 7.6.2.2

EC 7.6.2.3

XP_038399786.1

EC 7.6.2.2

EC 7.6.2.3

XP_038433897.1

EC 7.6.2.2

EC 7.6.2.3

XP_038433900.1

EC 7.6.2.2

EC 7.6.2.3

XP_038433903.1

EC 7.6.2.2

EC 7.6.2.3

XP_038463894.1

EC 7.6.2.2

EC 7.6.2.3

XP_038463895.1

EC 7.6.2.2

EC 7.6.2.3

XP_038463896.1

EC 7.6.2.2

EC 7.6.2.3

XP_038463897.1

EC 7.6.2.2

EC 7.6.2.3

XP_038528585.1

EC 7.6.2.2

EC 7.6.2.3

XP_038528586.1

EC 7.6.2.2

EC 7.6.2.3

XP_038528587.1

EC 7.6.2.2

EC 7.6.2.3

XP_038528588.1

EC 7.6.2.2

EC 7.6.2.3

XP_547670.1

EC 7.6.2.2

EC 7.6.2.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051811.1 Reference ROS_Cfam_1.0

Range

75516008..75571183

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038672658.1 → XP_038528586.1 ralA-binding protein 1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038672659.1 → XP_038528587.1 ralA-binding protein 1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038672657.1 → XP_038528585.1 ralA-binding protein 1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Related

ENSCAFP00845006467.1, ENSCAFT00845008229.1

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038672660.1 → XP_038528588.1 ralA-binding protein 1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049267.1 Alternate UMICH_Zoey_3.1

Range

75213986..75269336

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038482404.1 → XP_038338332.1 ralA-binding protein 1

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038482405.1 → XP_038338333.1 ralA-binding protein 1

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038482403.1 → XP_038338331.1 ralA-binding protein 1

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038482406.1 → XP_038338334.1 ralA-binding protein 1

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049748.1 Alternate UNSW_CanFamBas_1.0

Range

75231509..75286643

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038607967.1 → XP_038463895.1 ralA-binding protein 1

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038607968.1 → XP_038463896.1 ralA-binding protein 1

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038607966.1 → XP_038463894.1 ralA-binding protein 1

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038607969.1 → XP_038463897.1 ralA-binding protein 1

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049228.1 Alternate UU_Cfam_GSD_1.0

Range

75541877..75596810

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038543856.1 → XP_038399784.1 ralA-binding protein 1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038543857.1 → XP_038399785.1 ralA-binding protein 1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038543855.1 → XP_038399783.1 ralA-binding protein 1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038543858.1 → XP_038399786.1 ralA-binding protein 1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

74854142..74908610

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038577972.1 → XP_038433900.1 ralA-binding protein 1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_547670.7 → XP_547670.1 ralA-binding protein 1

See identical proteins and their annotated locations for XP_547670.1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038577969.1 → XP_038433897.1 ralA-binding protein 1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...
XM_038577975.1 → XP_038433903.1 ralA-binding protein 1

UniProtKB/TrEMBL

A0A8C0LI08, A0A8C0MB46, A0A8C0QDN5

Conserved Domains (2) summary

COG1196
Location:393 → 607

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd04381
Location:190 → 371

RhoGap_RalBP1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1 transiently ...