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SOAT1 sterol O-acyltransferase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 490325, updated on 5-Mar-2024

Summary

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Official Symbol
SOAT1provided by VGNC
Official Full Name
sterol O-acyltransferase 1provided by VGNC
Primary source
VGNC:VGNC:46646
See related
Ensembl:ENSCAFG00845005946
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (20217662..20292968, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (20005887..20081197, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (20368010..20443005, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (20126140..20201100, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (20232924..20307851, complement)

Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S6-like Neighboring gene axonemal dynein light chain domain containing 1 Neighboring gene inosine triphosphate pyrophosphatase-like Neighboring gene 60S ribosomal protein L23a-like Neighboring gene uncharacterized LOC119872668

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cholesterol O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cholesterol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fatty-acyl-CoA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol efflux IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sterol O-acyltransferase 1
Names
sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
XP_005622522.1
XP_013970628.1
XP_038336927.1
XP_038336928.1
XP_038336929.1
XP_038336930.1
XP_038398289.1
XP_038398290.1
XP_038398291.1
XP_038398292.1
XP_038421037.1
XP_038462448.1
XP_038462449.1
XP_038462450.1
XP_038462451.1
XP_038527117.1
XP_038527118.1
XP_038527119.1
XP_038527120.1
XP_547445.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051811.1 Reference ROS_Cfam_1.0

    Range
    20217662..20292968 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038671191.1 → XP_038527119.1  sterol O-acyltransferase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVM8, A0A8C0MDZ7, A0A8I3N1B2, A0A8P0NFS6
    Related
    ENSCAFP00845008252.1, ENSCAFT00845010596.1
    Conserved Domains (1) summary
    pfam03062
    Location:170 → 519
    MBOAT; membrane-bound O-acyltransferase family

  2. XM_038671189.1 → XP_038527117.1  sterol O-acyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MDZ7, A0A8I3N2Z1, A0A8P0SX12
    Related
    ENSCAFP00845008238.1, ENSCAFT00845010578.1
    Conserved Domains (1) summary
    pfam03062
    Location:190 → 539
    MBOAT; membrane-bound O-acyltransferase family

  3. XM_038671190.1 → XP_038527118.1  sterol O-acyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q9G5, A0A8I3N356
    Conserved Domains (1) summary
    pfam03062
    Location:173 → 522
    MBOAT; membrane-bound O-acyltransferase family

  4. XM_038671192.1 → XP_038527120.1  sterol O-acyltransferase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0Q9G5, A0A8I3N356
    Conserved Domains (1) summary
    pfam03062
    Location:138 → 487
    MBOAT; membrane-bound O-acyltransferase family

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049267.1 Alternate UMICH_Zoey_3.1

    Range
    20126140..20201100 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038481001.1 → XP_038336929.1  sterol O-acyltransferase 1 isoform X3

    Conserved Domains (1) summary
    pfam03062
    Location:170 → 519
    MBOAT; membrane-bound O-acyltransferase family

  2. XM_038480999.1 → XP_038336927.1  sterol O-acyltransferase 1 isoform X1

    Conserved Domains (1) summary
    pfam03062
    Location:190 → 539
    MBOAT; membrane-bound O-acyltransferase family

  3. XM_038481000.1 → XP_038336928.1  sterol O-acyltransferase 1 isoform X2

    Conserved Domains (1) summary
    pfam03062
    Location:173 → 522
    MBOAT; membrane-bound O-acyltransferase family

  4. XM_038481002.1 → XP_038336930.1  sterol O-acyltransferase 1 isoform X4

    Conserved Domains (1) summary
    pfam03062
    Location:138 → 487
    MBOAT; membrane-bound O-acyltransferase family

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

    Range
    20232924..20307851 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038606522.1 → XP_038462450.1  sterol O-acyltransferase 1 isoform X3

    Conserved Domains (1) summary
    pfam03062
    Location:170 → 519
    MBOAT; membrane-bound O-acyltransferase family

  2. XM_038606520.1 → XP_038462448.1  sterol O-acyltransferase 1 isoform X1

    Conserved Domains (1) summary
    pfam03062
    Location:190 → 539
    MBOAT; membrane-bound O-acyltransferase family

  3. XM_038606521.1 → XP_038462449.1  sterol O-acyltransferase 1 isoform X2

    Conserved Domains (1) summary
    pfam03062
    Location:173 → 522
    MBOAT; membrane-bound O-acyltransferase family

  4. XM_038606523.1 → XP_038462451.1  sterol O-acyltransferase 1 isoform X4

    Conserved Domains (1) summary
    pfam03062
    Location:138 → 487
    MBOAT; membrane-bound O-acyltransferase family

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

    Range
    20368010..20443005 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038542363.1 → XP_038398291.1  sterol O-acyltransferase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVM8, A0A8C0MDZ7, A0A8I3N1B2, A0A8P0NFS6
    Conserved Domains (1) summary
    pfam03062
    Location:170 → 519
    MBOAT; membrane-bound O-acyltransferase family

  2. XM_038542361.1 → XP_038398289.1  sterol O-acyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MDZ7, A0A8I3N2Z1, A0A8P0SX12
    Conserved Domains (1) summary
    pfam03062
    Location:190 → 539
    MBOAT; membrane-bound O-acyltransferase family

  3. XM_038542362.1 → XP_038398290.1  sterol O-acyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q9G5, A0A8I3N356
    Conserved Domains (1) summary
    pfam03062
    Location:173 → 522
    MBOAT; membrane-bound O-acyltransferase family

  4. XM_038542364.1 → XP_038398292.1  sterol O-acyltransferase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0Q9G5, A0A8I3N356
    Conserved Domains (1) summary
    pfam03062
    Location:138 → 487
    MBOAT; membrane-bound O-acyltransferase family

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    20005887..20081197 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_547445.7 → XP_547445.2  sterol O-acyltransferase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KVM8, A0A8C0MDZ7, A0A8I3N1B2, A0A8P0NFS6
    Conserved Domains (1) summary
    pfam03062
    Location:170 → 519
    MBOAT; membrane-bound O-acyltransferase family

  2. XM_005622465.4 → XP_005622522.1  sterol O-acyltransferase 1 isoform X1

    See identical proteins and their annotated locations for XP_005622522.1

    UniProtKB/TrEMBL
    A0A8C0MDZ7, A0A8I3N2Z1, A0A8P0SX12
    Conserved Domains (1) summary
    pfam03062
    Location:190 → 539
    MBOAT; membrane-bound O-acyltransferase family

  3. XM_038565109.1 → XP_038421037.1  sterol O-acyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Q9G5, A0A8I3N356
    Conserved Domains (1) summary
    pfam03062
    Location:173 → 522
    MBOAT; membrane-bound O-acyltransferase family

  4. XM_014115153.3 → XP_013970628.1  sterol O-acyltransferase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0Q9G5, A0A8I3N356
    Conserved Domains (1) summary
    pfam03062
    Location:138 → 487
    MBOAT; membrane-bound O-acyltransferase family
Nucleotide Protein
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