SOCS1 suppressor of cytokine signaling 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: SOCS1provided by VGNC
Official Full Name: suppressor of cytokine signaling 1provided by VGNC
Primary source: VGNC:VGNC:46648
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	6	NC_051810.1 (31692882..31694609)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	6	NC_006588.4 (32893176..32894903)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	6	NC_049227.1 (31804768..31806494)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	6	NC_049266.1 (31506103..31507841)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	6	NC_049747.1 (31380389..31382114)

Chromosome 6 - NC_051810.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phosphatidylinositol phosphate biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of phosphatidylinositol 3-kinase complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: suppressor of cytokine signaling 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051810.1 Reference ROS_Cfam_1.0

Range

31692882..31694609

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038667705.1 → XP_038523633.1 suppressor of cytokine signaling 1

UniProtKB/TrEMBL

A0A8C0Q0M0

Conserved Domains (2) summary

cd10382
Location:88 → 185

SH2_SOCS1; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins

cl02533
Location:189 → 231

SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049266.1 Alternate UMICH_Zoey_3.1

Range

31506103..31507841

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038480414.1 → XP_038336342.1 suppressor of cytokine signaling 1

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049747.1 Alternate UNSW_CanFamBas_1.0

Range

31380389..31382114

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038602999.1 → XP_038458927.1 suppressor of cytokine signaling 1

Conserved Domains (2) summary

cd10382
Location:88 → 185

SH2_SOCS1; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins

cl02533
Location:189 → 231

SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049227.1 Alternate UU_Cfam_GSD_1.0

Range

31804768..31806494

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038538873.1 → XP_038394801.1 suppressor of cytokine signaling 1

UniProtKB/TrEMBL

A0A8C0Q0M0

Conserved Domains (2) summary

cd10382
Location:88 → 185

SH2_SOCS1; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins

cl02533
Location:189 → 231

SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

32893176..32894903

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038533910.1 → XP_038389838.1 suppressor of cytokine signaling 1

UniProtKB/TrEMBL

A0A8C0Q0M0

Conserved Domains (2) summary

cd10382
Location:88 → 185

SH2_SOCS1; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins

cl02533
Location:189 → 231

SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...