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HIP1 huntingtin interacting protein 1 [ Canis lupus familiaris (dog) ]

Gene ID: 489814, updated on 5-Mar-2024

Summary

Official Symbol
HIP1provided by VGNC
Official Full Name
huntingtin interacting protein 1provided by VGNC
Primary source
VGNC:VGNC:41691
See related
Ensembl:ENSCAFG00845003838
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 6
Exon count:
33
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (6778147..6936340, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (8654406..8812467, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (6874374..7032555, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (6747968..6905918, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (6711133..6869280, complement)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene m7GpppX diphosphatase-like Neighboring gene uncharacterized LOC119879899 Neighboring gene carbonyl reductase [NADPH] 3-like Neighboring gene C-C motif chemokine ligand 26 Neighboring gene C-C motif chemokine ligand 24

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables clathrin adaptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables clathrin light chain binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phosphatidylinositol-3,4-bisphosphate binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phosphatidylinositol-3,5-bisphosphate binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in actin filament organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in clathrin coat assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in actin cortical patch IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in clathrin-coated vesicle IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extrinsic component of postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in presynapse IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
huntingtin-interacting protein 1; LOW QUALITY PROTEIN: huntingtin-interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    6778147..6936340 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038667924.1XP_038523852.1  huntingtin-interacting protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MV65, A0A8C0SH91, A0A8I3MQX2
    Related
    ENSCAFP00845005670.1, ENSCAFT00845007109.1
    Conserved Domains (5) summary
    smart00307
    Location:8131011
    ILWEQ; I/LWEQ domain
    COG1196
    Location:404644
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:527818
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam07651
    Location:39306
    ANTH; ANTH domain
    pfam16515
    Location:488580
    HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1
  2. XM_038667925.1XP_038523853.1  huntingtin-interacting protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0MV65, A0A8I3MNX4
    Related
    ENSCAFP00845005741.1, ENSCAFT00845007211.1
    Conserved Domains (5) summary
    smart00307
    Location:779977
    ILWEQ; I/LWEQ domain
    COG1196
    Location:370610
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:493784
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam07651
    Location:7272
    ANTH; ANTH domain
    pfam16515
    Location:454546
    HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1

RNA

  1. XR_005428210.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    6747968..6905918 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038477892.1XP_038333820.1  huntingtin-interacting protein 1 isoform X1

    Conserved Domains (5) summary
    smart00307
    Location:8131011
    ILWEQ; I/LWEQ domain
    COG1196
    Location:404644
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:527818
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam07651
    Location:39306
    ANTH; ANTH domain
    pfam16515
    Location:488580
    HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1
  2. XM_038477893.1XP_038333821.1  huntingtin-interacting protein 1 isoform X2

    Conserved Domains (5) summary
    smart00307
    Location:779977
    ILWEQ; I/LWEQ domain
    COG1196
    Location:370610
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:493784
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam07651
    Location:7272
    ANTH; ANTH domain
    pfam16515
    Location:454546
    HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1

RNA

  1. XR_005326666.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    6711133..6869280 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038603227.1XP_038459155.1  huntingtin-interacting protein 1 isoform X1

    Conserved Domains (5) summary
    smart00307
    Location:8131011
    ILWEQ; I/LWEQ domain
    COG1196
    Location:404644
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:527818
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam07651
    Location:39306
    ANTH; ANTH domain
    pfam16515
    Location:488580
    HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1
  2. XM_038603228.1XP_038459156.1  huntingtin-interacting protein 1 isoform X2

    Conserved Domains (5) summary
    smart00307
    Location:779977
    ILWEQ; I/LWEQ domain
    COG1196
    Location:370610
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:493784
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam07651
    Location:7272
    ANTH; ANTH domain
    pfam16515
    Location:454546
    HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1

RNA

  1. XR_005395076.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    6874374..7032555 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038539146.1XP_038395074.1  LOW QUALITY PROTEIN: huntingtin-interacting protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MV65

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8654406..8812467 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_546932.7XP_546932.3  huntingtin-interacting protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0MV65, A0A8C0SH91, A0A8I3MQX2
    Conserved Domains (5) summary
    smart00307
    Location:8131011
    ILWEQ; I/LWEQ domain
    COG1196
    Location:404644
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:527818
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam07651
    Location:39306
    ANTH; ANTH domain
    pfam16515
    Location:488580
    HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1
  2. XM_005620978.4XP_005621035.2  huntingtin-interacting protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0MV65, A0A8I3MNX4
    Conserved Domains (5) summary
    smart00307
    Location:779977
    ILWEQ; I/LWEQ domain
    COG1196
    Location:370610
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:493784
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam07651
    Location:7272
    ANTH; ANTH domain
    pfam16515
    Location:454546
    HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1

RNA

  1. XR_002627316.2 RNA Sequence