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MAP2K3 mitogen-activated protein kinase kinase 3 [ Canis lupus familiaris (dog) ]

Gene ID: 489547, updated on 5-Mar-2024

Summary

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Official Symbol
MAP2K3provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase 3provided by VGNC
Primary source
VGNC:VGNC:42961
See related
Ensembl:ENSCAFG00845026332
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (42839802..42869464)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (42870421..42900078)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (42946459..42976119)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (42806533..42836183)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (42753555..42783186)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial-like Neighboring gene uncharacterized LOC106558821 Neighboring gene N-acetyltransferase domain containing 1 Neighboring gene uncharacterized LOC102154017 Neighboring gene potassium inwardly rectifying channel subfamily J member 12 Neighboring gene lysine-rich nucleolar protein 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of Src signal transduction pathways in scatter factor-mediated cellular protection. Fan S, et al. J Biol Chem, 2009 Mar 20. PMID 19047046, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables MAP kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity mitogen-activated protein kinase kinase 3
XP_038331891.1
XP_038393080.1
XP_038457208.1
XP_038521774.1
XP_546666.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    42839802..42869464
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038665846.1 → XP_038521774.1  dual specificity mitogen-activated protein kinase kinase 3

    UniProtKB/TrEMBL
    A0A8C0L936, A0A8C0Q0W7, A0A8C0RB66
    Related
    ENSCAFP00845036454.1, ENSCAFT00845046424.1
    Conserved Domains (1) summary
    cd06617
    Location:62 → 344
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    42806533..42836183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038475963.1 → XP_038331891.1  dual specificity mitogen-activated protein kinase kinase 3

    Conserved Domains (1) summary
    cd06617
    Location:62 → 344
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    42753555..42783186
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038601280.1 → XP_038457208.1  dual specificity mitogen-activated protein kinase kinase 3

    Conserved Domains (1) summary
    cd06617
    Location:62 → 344
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    42946459..42976119
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038537152.1 → XP_038393080.1  dual specificity mitogen-activated protein kinase kinase 3

    UniProtKB/TrEMBL
    A0A8C0L936, A0A8C0Q0W7, A0A8C0RB66
    Conserved Domains (1) summary
    cd06617
    Location:62 → 344
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    42870421..42900078
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_546666.6 → XP_546666.2  dual specificity mitogen-activated protein kinase kinase 3

    UniProtKB/TrEMBL
    A0A8C0L936, A0A8C0Q0W7, A0A8C0RB66
    Conserved Domains (1) summary
    cd06617
    Location:62 → 344
    PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6
Nucleotide Protein
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