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ALOX15B arachidonate 15-lipoxygenase type B [ Canis lupus familiaris (dog) ]

Gene ID: 489485, updated on 5-Mar-2024

Summary

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Official Symbol
ALOX15Bprovided by VGNC
Official Full Name
arachidonate 15-lipoxygenase type Bprovided by VGNC
Primary source
VGNC:VGNC:37812
See related
Ensembl:ENSCAFG00845027303
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (32981218..32991101)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (33014628..33024494)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (33084046..33093901)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (32948241..32958102)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (32904002..32913858)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene centrobin, centriole duplication and spindle assembly protein Neighboring gene trafficking protein particle complex subunit 1 Neighboring gene guanylate cyclase 2D, retinal Neighboring gene arachidonate 12-lipoxygenase, 12R type Neighboring gene arachidonate lipoxygenase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 15-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 15-lipoxygenase B; polyunsaturated fatty acid lipoxygenase ALOX15B
XP_038333564.1
XP_038333565.1
XP_038360479.1
XP_038391450.1
XP_038391451.1
XP_038455672.1
XP_038455673.1
XP_038520201.1
XP_038520202.1
XP_546603.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    32981218..32991101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038664274.1 → XP_038520202.1  polyunsaturated fatty acid lipoxygenase ALOX15B isoform X2

    UniProtKB/TrEMBL
    A0A8C0K384, A0A8C0NH48
    Conserved Domains (2) summary
    cd01753
    Location:2 → 122
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:233 → 613
    Lipoxygenase

  2. XM_038664273.1 → XP_038520201.1  polyunsaturated fatty acid lipoxygenase ALOX15B isoform X1

    UniProtKB/TrEMBL
    A0A8C0K384, A0A8C0NH48, A0A8C0QDK5, A0A8I3Q2D9
    Related
    ENSCAFP00845037862.1, ENSCAFT00845048267.1
    Conserved Domains (2) summary
    cd01753
    Location:2 → 122
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:233 → 668
    Lipoxygenase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    32948241..32958102
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038477637.1 → XP_038333565.1  polyunsaturated fatty acid lipoxygenase ALOX15B isoform X2

    Conserved Domains (2) summary
    cd01753
    Location:2 → 122
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:233 → 613
    Lipoxygenase

  2. XM_038477636.1 → XP_038333564.1  polyunsaturated fatty acid lipoxygenase ALOX15B isoform X1

    Conserved Domains (2) summary
    cd01753
    Location:2 → 122
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:233 → 668
    Lipoxygenase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    32904002..32913858
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038599745.1 → XP_038455673.1  polyunsaturated fatty acid lipoxygenase ALOX15B isoform X2

    Conserved Domains (2) summary
    cd01753
    Location:2 → 122
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:233 → 613
    Lipoxygenase

  2. XM_038599744.1 → XP_038455672.1  polyunsaturated fatty acid lipoxygenase ALOX15B isoform X1

    Conserved Domains (2) summary
    cd01753
    Location:2 → 122
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:233 → 668
    Lipoxygenase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    33084046..33093901
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535523.1 → XP_038391451.1  polyunsaturated fatty acid lipoxygenase ALOX15B isoform X2

    UniProtKB/TrEMBL
    A0A8C0K384, A0A8C0NH48
    Conserved Domains (2) summary
    cd01753
    Location:2 → 122
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:233 → 613
    Lipoxygenase

  2. XM_038535522.1 → XP_038391450.1  polyunsaturated fatty acid lipoxygenase ALOX15B isoform X1

    UniProtKB/TrEMBL
    A0A8C0K384, A0A8C0NH48, A0A8C0QDK5, A0A8I3Q2D9
    Conserved Domains (2) summary
    cd01753
    Location:2 → 122
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:233 → 668
    Lipoxygenase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    33014628..33024494
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038504551.1 → XP_038360479.1  polyunsaturated fatty acid lipoxygenase ALOX15B isoform X2

    UniProtKB/TrEMBL
    A0A8C0K384, A0A8C0NH48
    Conserved Domains (2) summary
    cd01753
    Location:2 → 122
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:233 → 613
    Lipoxygenase

  2. XM_546603.4 → XP_546603.2  polyunsaturated fatty acid lipoxygenase ALOX15B isoform X1

    UniProtKB/TrEMBL
    A0A8C0K384, A0A8C0NH48, A0A8C0QDK5, A0A8I3Q2D9
    Conserved Domains (2) summary
    cd01753
    Location:2 → 122
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:233 → 668
    Lipoxygenase
Nucleotide Protein
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