ALOX15 arachidonate 15-lipoxygenase [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ALOX15provided by VGNC
Official Full Name: arachidonate 15-lipoxygenaseprovided by VGNC
Primary source: VGNC:VGNC:37811
See related: Ensembl:ENSCAFG00845016761
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
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Genomic context

Location:: chromosome: 5

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	5	NC_051809.1 (31988523..31996819)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	5	NC_006587.4 (32022707..32030999)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	5	NC_049226.1 (32090734..32099028)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	5	NC_049265.1 (31954788..31963077)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	5	NC_049746.1 (31914466..31922749)

Chromosome 5 - NC_051809.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables arachidonate 12(S)-lipoxygenase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables arachidonate 15-lipoxygenase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables iron ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in linoleic acid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in lipid oxidation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: polyunsaturated fatty acid lipoxygenase ALOX15

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051809.1 Reference ROS_Cfam_1.0

Range

31988523..31996819

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038665319.1 → XP_038521247.1 polyunsaturated fatty acid lipoxygenase ALOX15

UniProtKB/TrEMBL

A0A8C0KD82, A0A8C0KDR8, A0A8C0MQI7, A0A8I3P5X5

Related

ENSCAFP00845023346.1, ENSCAFT00845029723.1

Conserved Domains (2) summary

cd01753
Location:2 → 112

PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...

pfam00305
Location:162 → 654

Lipoxygenase

Alternate UMICH_Zoey_3.1

Genomic

NC_049265.1 Alternate UMICH_Zoey_3.1

Range

31954788..31963077

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038475423.1 → XP_038331351.1 polyunsaturated fatty acid lipoxygenase ALOX15

Conserved Domains (2) summary

cd01753
Location:2 → 112

PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...

pfam00305
Location:162 → 654

Lipoxygenase

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049746.1 Alternate UNSW_CanFamBas_1.0

Range

31914466..31922749

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038600785.1 → XP_038456713.1 polyunsaturated fatty acid lipoxygenase ALOX15

Conserved Domains (2) summary

cd01753
Location:2 → 112

PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...

pfam00305
Location:162 → 654

Lipoxygenase

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049226.1 Alternate UU_Cfam_GSD_1.0

Range

32090734..32099028

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038536592.1 → XP_038392520.1 polyunsaturated fatty acid lipoxygenase ALOX15

UniProtKB/TrEMBL

A0A8C0KD82

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

32022707..32030999

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_546576.6 → XP_546576.2 polyunsaturated fatty acid lipoxygenase ALOX15

UniProtKB/TrEMBL

A0A8C0KD82, A0A8C0KDR8, A0A8C0MQI7, A0A8I3P5X5

Conserved Domains (2) summary

cd01753
Location:2 → 112

PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...

pfam00305
Location:162 → 654

Lipoxygenase