MMP27 matrix metallopeptidase 27 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: MMP27provided by VGNC
Official Full Name: matrix metallopeptidase 27provided by VGNC
Primary source: VGNC:VGNC:43286
See related: Ensembl:ENSCAFG00845000933
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	5	NC_051809.1 (29102601..29115773)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	5	NC_006587.4 (28999656..29012832)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	5	NC_049226.1 (29192029..29205191)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	5	NC_049265.1 (29137639..29150750)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	5	NC_049746.1 (29016829..29030018)

Chromosome 5 - NC_051809.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables metalloendopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in collagen catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in extracellular matrix organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular matrix	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: matrix metalloproteinase-27; LOW QUALITY PROTEIN: matrix metalloproteinase-27

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051809.1 Reference ROS_Cfam_1.0

Range

29102601..29115773

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038664270.1 → XP_038520198.1 matrix metalloproteinase-27

UniProtKB/TrEMBL

A0A8C0K9J2, A0A8C0N895, A0A8I3RR56

Related

ENSCAFP00845001253.1, ENSCAFT00845001583.1

Conserved Domains (3) summary

cd00094
Location:277 → 465

HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...

pfam00413
Location:106 → 261

Peptidase_M10; Matrixin

pfam01471
Location:26 → 86

PG_binding_1; Putative peptidoglycan binding domain

Alternate UMICH_Zoey_3.1

Genomic

NC_049265.1 Alternate UMICH_Zoey_3.1

Range

29137639..29150750

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038477631.1 → XP_038333559.1 LOW QUALITY PROTEIN: matrix metalloproteinase-27

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049746.1 Alternate UNSW_CanFamBas_1.0

Range

29016829..29030018

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038600560.1 → XP_038456488.1 matrix metalloproteinase-27

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049226.1 Alternate UU_Cfam_GSD_1.0

Range

29192029..29205191

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038536354.1 → XP_038392282.1 matrix metalloproteinase-27

UniProtKB/TrEMBL

A0A8C0K9J2, A0A8C0N895, A0A8I3RR56

Conserved Domains (3) summary

cd00094
Location:277 → 465

HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...

pfam00413
Location:106 → 261

Peptidase_M10; Matrixin

pfam01471
Location:26 → 86

PG_binding_1; Putative peptidoglycan binding domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

28999656..29012832

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_546548.6 → XP_546548.2 matrix metalloproteinase-27

See identical proteins and their annotated locations for XP_546548.2

UniProtKB/TrEMBL

A0A8C0K9J2, A0A8P0NGJ3

Conserved Domains (4) summary

cd00094
Location:277 → 465

HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...

cd04278
Location:106 → 261

ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...

pfam00413
Location:106 → 261

Peptidase_M10; Matrixin

pfam01471
Location:26 → 86

PG_binding_1; Putative peptidoglycan binding domain