U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MMP8 matrix metallopeptidase 8 [ Canis lupus familiaris (dog) ]

Gene ID: 489429, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
MMP8provided by VGNC
Official Full Name
matrix metallopeptidase 8provided by VGNC
Primary source
VGNC:VGNC:43289
See related
Ensembl:ENSCAFG00845000899
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 5
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (29087831..29098581)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (28984875..28995648)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (29177264..29188014)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (29122825..29133583)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (29002064..29012820)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene stromelysin-1-like Neighboring gene interstitial collagenase-like Neighboring gene matrix metallopeptidase 27 Neighboring gene matrix metallopeptidase 20

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
neutrophil collagenase
Names
matrix metallopeptidase 8 (neutrophil collagenase)
XP_038331140.1
XP_038392281.1
XP_038456487.1
XP_038521019.1
XP_546547.3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    29087831..29098581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038665091.1 → XP_038521019.1  neutrophil collagenase

    UniProtKB/TrEMBL
    A0A8C0K9M4, A0A8I3MXC2, A0A8P0SJK1
    Related
    ENSCAFP00845001189.1, ENSCAFT00845001511.1
    Conserved Domains (3) summary
    cd00094
    Location:287 → 475
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam00413
    Location:118 → 273
    Peptidase_M10; Matrixin
    pfam01471
    Location:42 → 97
    PG_binding_1; Putative peptidoglycan binding domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    29122825..29133583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038475212.1 → XP_038331140.1  neutrophil collagenase

    Conserved Domains (3) summary
    cd00094
    Location:287 → 475
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam00413
    Location:118 → 273
    Peptidase_M10; Matrixin
    pfam01471
    Location:42 → 97
    PG_binding_1; Putative peptidoglycan binding domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    29002064..29012820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038600559.1 → XP_038456487.1  neutrophil collagenase

    Conserved Domains (3) summary
    cd00094
    Location:287 → 475
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam00413
    Location:118 → 273
    Peptidase_M10; Matrixin
    pfam01471
    Location:42 → 97
    PG_binding_1; Putative peptidoglycan binding domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    29177264..29188014
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038536353.1 → XP_038392281.1  neutrophil collagenase

    UniProtKB/TrEMBL
    A0A8C0K9M4, A0A8I3MXC2, A0A8P0SJK1
    Conserved Domains (3) summary
    cd00094
    Location:287 → 475
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam00413
    Location:118 → 273
    Peptidase_M10; Matrixin
    pfam01471
    Location:42 → 97
    PG_binding_1; Putative peptidoglycan binding domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    28984875..28995648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_546547.7 → XP_546547.3  neutrophil collagenase

    UniProtKB/TrEMBL
    A0A8C0K9M4, A0A8I3MXC2, A0A8P0SJK1
    Conserved Domains (3) summary
    cd00094
    Location:287 → 475
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam00413
    Location:118 → 273
    Peptidase_M10; Matrixin
    pfam01471
    Location:42 → 97
    PG_binding_1; Putative peptidoglycan binding domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.