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ITGA1 integrin subunit alpha 1 [ Canis lupus familiaris (dog) ]

Gene ID: 489210, updated on 5-Mar-2024

Summary

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Official Symbol
ITGA1provided by VGNC
Official Full Name
integrin subunit alpha 1provided by VGNC
Primary source
VGNC:VGNC:42120
See related
Ensembl:ENSCAFG00845000521
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ITGA1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
29
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (62785836..62953966, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (62062740..62230868, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (63212383..63380850, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (62561013..62729609, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (62685631..62847651, complement)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene integrin subunit alpha 2 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene 60S ribosomal protein L36a-like Neighboring gene uncharacterized LOC119871537 Neighboring gene pelota mRNA surveillance and ribosome rescue factor Neighboring gene uncharacterized LOC111095611 Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    62785836..62953966 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038663735.1 → XP_038519663.1  integrin alpha-1

    UniProtKB/TrEMBL
    A0A8C0LH09, A0A8C0R6E3, A0A8C0S0A1, A0A8I3MAW3
    Related
    ENSCAFP00845000638.1, ENSCAFT00845000849.1
    Conserved Domains (3) summary
    smart00191
    Location:567 → 620
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:171 → 351
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:663 → 1072
    Integrin_alpha2; Integrin alpha

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    62561013..62729609 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038474032.1 → XP_038329960.1  integrin alpha-1

    Conserved Domains (3) summary
    smart00191
    Location:567 → 620
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:171 → 351
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:663 → 1072
    Integrin_alpha2; Integrin alpha

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    62685631..62847651 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038599425.1 → XP_038455353.1  integrin alpha-1

    Conserved Domains (3) summary
    smart00191
    Location:567 → 620
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:171 → 351
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:663 → 1072
    Integrin_alpha2; Integrin alpha

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    63212383..63380850 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535131.1 → XP_038391059.1  integrin alpha-1

    UniProtKB/TrEMBL
    A0A8C0LH09, A0A8C0R6E3, A0A8C0S0A1, A0A8I3MAW3
    Conserved Domains (3) summary
    smart00191
    Location:567 → 620
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:171 → 351
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:663 → 1072
    Integrin_alpha2; Integrin alpha

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    62062740..62230868 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005619335.4 → XP_005619392.1  integrin alpha-1

    UniProtKB/TrEMBL
    A0A8C0LH09, A0A8C0R6E3, A0A8C0S0A1, A0A8I3MAW3
    Conserved Domains (3) summary
    smart00191
    Location:567 → 620
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:171 → 351
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:663 → 1072
    Integrin_alpha2; Integrin alpha
Nucleotide Protein
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